COMP <GO>
AVTX vs PRTA // FORWARD P/E MULTIPLE
Avalo Therapeutics Inc. (NASDAQ) VS. Prothena Corporation plc (NASDAQ) • 15-METRIC TALLY: AVTX 1
— PRTA 2
■ METRIC PARITY
LAST: $7.17 (-3.63%) • MKT CAP: $384.5M
forward-pe
—
LAST: $8.47 (-4.62%) • MKT CAP: $434.8M
forward-pe
—
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (AVTX VS. PRTA)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | AVTX | PRTA | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin | — | — | — | TIE | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | -35.00% | -35.00% | 0.00 | TIE | /roic <GO> |
| EV/EBITDA & P/E Valuation | — | — | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | -12.90% | — | — | TIE | /fcf-yield <GO> |
| Operating Margin | -60.00% | -60.00% | 0.00 | TIE | /operating-margins <GO> |
| Net Profit Margin | -60.00% | -60.00% | 0.00 | TIE | /net-margins <GO> |
| Revenue Growth (YoY) | -65.00% | -65.00% | 0.00 | TIE | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 0.00% | 0.00 | TIE | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | 0.66 | 0.20 | +0.46 | AVTX | /balance-sheet <GO> |
| Piotroski F-Score Quality | 2/9 | 2/9 | 0.00 | TIE | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 24.4 | 48.3 | -23.90 | PRTA | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | — | — | — | TIE | /macro-sensitivity <GO> |
| Forward P/E Multiple ACTIVE | — | — | — | TIE | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $384.5M | $434.8M | -$50.3M | PRTA | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | AVTX REV | PRTA REV | AVTX GROSS % | PRTA GROSS % | AVTX FCF | PRTA FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $59.0K | $9.7M | — | — | -$51.5M | -$163.6M |
| FY 2024 | $441.0K | $135.2M | — | — | -$49.1M | -$150.1M |
| FY 2023 | $1.9M | $91.4M | — | — | -$30.7M | -$133.9M |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
AVTX // BETA —
PRTA // BETA —