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BCYC vs GLSI // 10Y YIELD & FRED MACRO BETA

Bicycle Therapeutics plc (NASDAQ) VS. Greenwich LifeSciences Inc. (NASDAQ) • 15-METRIC TALLY: BCYC 1 — GLSI 1
■ METRIC PARITY
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (BCYC VS. GLSI) EMERALD CELL = QUANTITATIVE EDGE
INSTITUTIONAL METRIC BCYC GLSI SPREAD (A - B) ADVANTAGE DEDICATED URL
Gross Profit Margin — — — TIE /gross-margins <GO>
Return on Invested Capital (ROIC) -35.00% -35.00% 0.00 TIE /roic <GO>
EV/EBITDA & P/E Valuation — — — TIE /valuation <GO>
Free Cash Flow Yield — -3.55% — TIE /fcf-yield <GO>
Operating Margin -60.00% — — TIE /operating-margins <GO>
Net Profit Margin -60.00% — — TIE /net-margins <GO>
Revenue Growth (YoY) 105.80% — — TIE /revenue-growth <GO>
Dividend Yield & FCF Payout Safety 0.00% 0.00% 0.00 TIE /dividend-safety <GO>
Altman Z-Score & Debt/Equity 0.20 — — TIE /balance-sheet <GO>
Piotroski F-Score Quality 2/9 2/9 0.00 TIE /piotroski-score <GO>
Options Implied Move & Put/Call Skew — — — TIE /options-implied-move <GO>
RSI-14 & 200D SMA Momentum 48.1 51.8 -3.70 GLSI /rsi-technicals <GO>
10Y Yield & FRED Macro Beta ACTIVE — — — TIE /macro-sensitivity <GO>
Forward P/E Multiple — — — TIE /forward-pe <GO>
Enterprise Scale & Market Cap $256.5M $255.5M $995.6K BCYC /market-cap <GO>
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
FISCAL YEAR BCYC REV GLSI REV BCYC GROSS % GLSI GROSS % BCYC FCF GLSI FCF
FY 2025 $72.6M $54.5M — — -$252.0M -$9.9M
FY 2024 $35.3M $49.4M — — -$166.0M -$7.3M
FY 2023 $27.0M $26.1M — — -$60.6M -$6.5M
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
BCYC // BETA —
GLSI // BETA —