COMP <GO>
PTGX vs MRK // EV/EBITDA & P/E VALUATION
Protagonist Therapeutics Inc. (NASDAQ) VS. Merck & Company Inc. (NYSE) • 15-METRIC TALLY: PTGX 3
— MRK 9
■ METRIC PARITY
LAST: $139.37 (-3.78%) • MKT CAP: $9.37B
valuation
—
LAST: $148.36 (-0.78%) • MKT CAP: $368.89B
valuation
15.3x
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (PTGX VS. MRK)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | PTGX | MRK | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin | — | 74.80% | — | TIE | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | -16.70% | 20.70% | -37.40 | MRK | /roic <GO> |
| EV/EBITDA & P/E Valuation ACTIVE | — | 15.3x | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | 0.60% | 3.42% | -2.82 | MRK | /fcf-yield <GO> |
| Operating Margin | -6.00% | 34.30% | -40.30 | MRK | /operating-margins <GO> |
| Net Profit Margin | -5.00% | 28.10% | -33.10 | MRK | /net-margins <GO> |
| Revenue Growth (YoY) | 0.00% | 1.30% | -1.30 | MRK | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 2.26% | -2.26 | MRK | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | 26.00 | 5.19 | +20.81 | PTGX | /balance-sheet <GO> |
| Piotroski F-Score Quality | 6/9 | 7/9 | -1.00 | MRK | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 57.7 | 56.3 | +1.40 | PTGX | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | 0.99 | 0.92 | +0.07 | PTGX | /macro-sensitivity <GO> |
| Forward P/E Multiple | 31.0x | 18.4x | +12.60 | MRK | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $9.37B | $368.89B | -$359.52B | MRK | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | PTGX REV | MRK REV | PTGX GROSS % | MRK GROSS % | PTGX FCF | MRK FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $442.8M | $65.01B | — | 74.8% | $56.1M | $12.36B |
| FY 2024 | $708.0M | $64.17B | — | 76.3% | $182.8M | $18.10B |
| FY 2023 | $262.2M | $60.12B | — | — | -$70.2M | $10.30B |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
PTGX // BETA 0.99
MRK // BETA 0.92