COMP <GO>
SEPN vs ZYME // FORWARD P/E MULTIPLE
Septerna Inc. (NASDAQ) VS. Zymeworks Inc. (NASDAQ) • 15-METRIC TALLY: SEPN 6
— ZYME 1
■ METRIC PARITY
LAST: $44.00 (-2.72%) • MKT CAP: $2.05B
forward-pe
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LAST: $28.61 (-0.35%) • MKT CAP: $2.02B
forward-pe
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15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (SEPN VS. ZYME)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | SEPN | ZYME | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin | — | — | — | TIE | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | -20.70% | -32.20% | +11.50 | SEPN | /roic <GO> |
| EV/EBITDA & P/E Valuation | — | — | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | 5.19% | -1.71% | +6.90 | SEPN | /fcf-yield <GO> |
| Operating Margin | -60.00% | -60.00% | 0.00 | TIE | /operating-margins <GO> |
| Net Profit Margin | -60.00% | -60.00% | 0.00 | TIE | /net-margins <GO> |
| Revenue Growth (YoY) | 180.00% | 38.90% | +141.10 | SEPN | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 0.00% | 0.00 | TIE | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | 5.87 | 11.85 | -5.98 | ZYME | /balance-sheet <GO> |
| Piotroski F-Score Quality | 6/9 | 4/9 | +2.00 | SEPN | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 62.4 | 60.0 | +2.40 | SEPN | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | — | — | — | TIE | /macro-sensitivity <GO> |
| Forward P/E Multiple ACTIVE | — | — | — | TIE | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $2.05B | $2.02B | $37.5M | SEPN | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | SEPN REV | ZYME REV | SEPN GROSS % | ZYME GROSS % | SEPN FCF | ZYME FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $46.0M | $106.0M | — | — | $109.7M | -$34.5M |
| FY 2024 | $1.1M | $76.3M | — | — | -$69.6M | -$112.0M |
| FY 2023 | $151.0K | $76.0M | — | — | -$38.7M | -$118.3M |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
SEPN // BETA —
ZYME // BETA —