Yahoo! Finance Canada report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Why ADAG Stock dropped -8.76% Today — RQD Quant Desk Flash
Adagene Inc. (ADAG) carries a Roarable Rating of E (Strong Sell) with 25/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief)
Is ADAG stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-03, Adagene Inc. (NASDAQ: ADAG) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 25/100 at a spot price of $2.29 (-8.76% 1D, market cap $151.3M). Pillar breakdown: Fundamental Cash Engine 3/20, Institutional 13F & Options Flow 4/20, SEC Balance-Sheet Forensics 8/20, FRED Macro Regime Fit 7/20, and Executive Insider Alignment 3/20. Across 1015 tracked Health Care issuers, ADAG ranks #925 in composite RQD confidence.
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief)
How does ADAG compare to MGNX and RNA in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), ADAG carries a Roarable E (25/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, MGNX (MacroGenics Inc.) holds a E grade (24/100 RQD, P/E N/A, ROIC -35.0%, cap $148.4M) and RNA (Atrium Therapeutics Inc.) posts a D grade (44/100 RQD, P/E N/A, ROIC —, cap $146.3M). Among the 5-stock peer group, ADAG leads on earnings multiple (N/A) while ADAG leads on capital efficiency (-35.0% ROIC).
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief)
What are the biggest fundamental strengths and SEC risk factors for ADAG?
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Per ADAG's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001818838), Adagene Inc. generated $7.7M in revenue (+7332.8% YoY), -$17.6M in net income, and -$15.7M in free cash flow against $78.3M in total assets and $1.1M in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
Altman Z-Score 0.20 (DISTRESS RISK (<1.8)) • Piotroski F-Score 5/9
FRED Regime × Technicals: 28% of 52W Range • RSI-14 at 37.5 (NEUTRAL RANGE)
Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment
⚔️ Adversarial Opposing Case: What Could Spark a ADAG Turnaround Squeeze
While ADAG currently carries a cautious 25/100 (E) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
Established market leader in Health Care with deep daily trading liquidity.
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($2.99) and Max Pain ($2.40) forces dealer call-delta covering toward $5.09.
Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
Why ADAG Stock dropped -8.76% Today — RQD Quant Desk Flash
Adagene Inc. (ADAG) dropped -8.76% to $2.29, trading at 28% of its 52-week range ($1.3 – $4.85). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 28% of its 52-week range ($1.3 – $4.85) with RSI-14 at 37.5 (NEUTRAL RANGE).
- ▸Volatility Profile: Historical 20-day realized swing band of ±12.5% around $2.29 (no active unusual options sweep snapshot on file).
- ▸Fundamental Anchor: Roarable E (Strong Sell) backed by 52% gross margin and $0 annual free cash flow.
StockInvest.us report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
https://www.dars.gov.et/ report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Traders Union report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Incyte (NasdaqGS: INCY) and Adagene have started first patient dosing in a Phase 1 trial combining INCA33890 with muzastotug for microsatellite stable colorectal cancer. The early stage study is testing the investigation
Phase 1 study to evaluate the combination of muzastotug, a masked anti-CTLA-4 SAFEbody, and INCA33890, Incyte’s TGFβR2 × PD-1 bispecific antibody, in 3L MSS CRC patients with and without liver metastases SAN DIEGO and SU
Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring ADAG)
- ✓Walkthrough of ADAG's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
- ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
ADAG Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. +7332.8% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on ADAG today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for ADAG. Explore sector supply chains on /butterfly.
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (ADAG)
1. Head-to-Head Health Care Peer Comparison (ADAG vs. MGNX, RNA, VRXA, NGEN)
Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)Across 1015 tracked Health Care securities in the Roarable RQD universe, Adagene Inc. (ADAG) ranks #925 by composite RQD confidence (25/100, grade E) and #600 by equity capitalization ($151.3M). Within this direct 5-issuer industry benchmark cohort, ADAG leads on earnings valuation at N/A trailing P/E, while ADAG leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. VRXA currently holds the highest overall quantitative score in the immediate peer group at 49/100 (D) compared with ADAG at 25/100 (E).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| ADAG
ACTIVE
Adagene Inc. | E | 25/100 | — | — | -35.0% | -8.76% | $151.3M | Benchmark Subject |
| MGNX MacroGenics Inc. | E | 24/100 | — | 96.0% | -35.0% | -2.92% | $148.4M | /mgnx-vs-adag → |
| RNA Atrium Therapeutics Inc. | D | 44/100 | — | — | — | +3.39% | $146.3M | /rna-vs-adag → |
| VRXA Veraxa Biotech AG | D | 49/100 | — | — | — | -9.65% | $145.7M | /vrxa-vs-adag → |
| NGEN NervGen Pharma Corp. | D | 45/100 | — | — | — | -1.46% | $145.3M | /ngen-vs-adag → |
2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)
SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001818838 ↗In its most recent audited fiscal period (FY2025, filed 2025-12-31), Adagene Inc. (ADAG) reported GAAP revenue of $7.7M (+7332.8% vs. FY2024 revenue of $103.2K , and -57.6% cumulative change since FY2023) , GAAP net income of -$17.6M, operating cash flow of -$15.7M, and free cash flow of -$15.7M (+47.3% YoY). On the balance sheet, ADAG closed FY2025 with $78.3M in total assets against $1.1M in total debt (Altman Z-Score: 0.20, Piotroski F-Score: 5/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $7.7M | -$17.6M | -$15.7M | -$15.7M | $78.3M | $1.1M |
| FY2024 (FY) | 2024-12-31 | $103.2K | -$33.4M | -$29.7M | -$29.7M | $89.3M | $417.3K |
| FY2023 (FY) | 2023-12-31 | $18.1M | -$18.9M | -$28.5M | -$28.5M | — | — |
3. ADAG Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs ADAG stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-03, Adagene Inc. (NASDAQ: ADAG) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 25/100 at a spot price of $2.29 (-8.76% 1D, market cap $151.3M). Pillar breakdown: Fundamental Cash Engine 3/20, Institutional 13F & Options Flow 4/20, SEC Balance-Sheet Forensics 8/20, FRED Macro Regime Fit 7/20, and Executive Insider Alignment 3/20. Across 1015 tracked Health Care issuers, ADAG ranks #925 in composite RQD confidence.
How does ADAG compare to MGNX and RNA in the Health Care sector?
Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), ADAG carries a Roarable E (25/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, MGNX (MacroGenics Inc.) holds a E grade (24/100 RQD, P/E N/A, ROIC -35.0%, cap $148.4M) and RNA (Atrium Therapeutics Inc.) posts a D grade (44/100 RQD, P/E N/A, ROIC —, cap $146.3M). Among the 5-stock peer group, ADAG leads on earnings multiple (N/A) while ADAG leads on capital efficiency (-35.0% ROIC).
What are the biggest fundamental strengths and SEC risk factors for ADAG?
Per ADAG's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001818838), Adagene Inc. generated $7.7M in revenue (+7332.8% YoY), -$17.6M in net income, and -$15.7M in free cash flow against $78.3M in total assets and $1.1M in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Where is ADAG trading relative to its 50-day, 200-day, and 52-week technical levels?
ADAG last traded at $2.29 (-8.76% on volume of 181,781 shares), positioning the stock -23.41% below its 50-day simple moving average ($2.99) and -33.24% below its 200-day simple moving average ($3.43). Across its 52-week range of $1.30 to $4.85, ADAG sits at the 27.9% percentile with a 14-day RSI of 37.5 (NEUTRAL RANGE) and an implied next-earnings move of ±12.5% ($2.00 to $2.58).
ADAG — Adagene Inc.: What the Facts Mean to a Prospective Investor
1. Roarable Rating Brief: What This Means to a Prospective Investor
Adagene Inc. (ADAG) earns a live Roarable RQD composite score of 25/100, corresponding to a E letter grade (Roarable Strong Sell) at a spot price of $2.29 (-8.76% 1D, market capitalization $151.3M).
- Fundamental Cash Engine (3/20): Anchored by return on invested capital (ROIC) of -35.0%, gross margin of —, operating margin of -60.0%, and free cash flow yield of -8.85%.
- Whale 13F & Options Flow (4/20) + Insider Conviction (3/20): Tracks institutional 13F accumulation, CBOE options call/put positioning, and SEC Form 4 / Congressional PTR filings.
- Macro Regime Fit (7/20) + Forensic Balance Sheet (8/20): Incorporates a 1.00x equity beta, Altman Z-Score of 0.20, Piotroski F-Score of 5/9, and Debt/Equity of 0.03x.
2. Business Model, Unit Margins & SEC Financial Trajectory
Adagene Inc. Is a NASDAQ-listed issuer in the Health Care sector, within the Biotechnology: Pharmaceutical Preparations industry, . The profile describes it as operating with a market capitalization of $0.2B.
In its latest audited SEC EDGAR 10-K filing for FY2025 (filed 2025-12-31), Adagene Inc. (ADAG) reported $7.7M in annual revenue (up from $103.2K in FY2024, +7332.8% YoY) and -$17.6M in GAAP net income. Over the multi-year SEC filing window from FY2023 ($18.1M revenue, -$18.9M net income) through FY2025, ADAG scaled operating cash flow to -$15.7M and free cash flow to -$15.7M, backed by $78.3M in total assets against $1.1M in total debt.
3. Institutional Bull vs. Bear Thesis & Valuation Tradeoff
- 🐂 Primary Bull Case (E • RQD 25/100): Established market leader in Health Care with deep daily trading liquidity. Free cash flow yield of -8.85% and institutional whale pillar of 4/20. With Fundamental Cash Engine at 3/20 and Institutional Whale Flow at 4/20, sustained execution supports upside toward the upper end of the $1.30 – $4.85 52-week range.
- 🐻 Primary Bear Case & Valuation Risk: Company executives have done more routine share selling than personal cash buying lately. Investors must weigh current valuation against -60.0% operating margins and a 1.00x macro beta.
4. 2nd-Order Butterfly Ripples & Key Questions to Watch
Operating in Biotechnology: Pharmaceutical Preparations (Health Care), ADAG carries a macro regime beta of 1.00 and gross margin of —.
- Key Question #1: Can ADAG sustain or expand its -60.0% operating margin and -35.0% ROIC against Biotechnology: Pharmaceutical Preparations peers over the next 4 quarters?
- Key Question #2: Following FY2025 revenue of $7.7M and free cash flow of -$15.7M, how will capital allocation balance growth reinvestment against $1.1M in total debt?
- Key Question #3: How sensitive is ADAG's equity valuation to Health Care capital spending cycles and macro interest-rate shifts (Beta 1.00x)?
ADAG Live News Feed, Press Releases & Catalyst Wire
Real-time company headlines, analyst actions, and sector developments for Adagene Inc. (ADAG) • Click "Debate This Headline" to argue it in the Roar Pit below
Yahoo! Finance Canada report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
StockInvest.us report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
https://www.dars.gov.et/ report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
Traders Union report covering Adagene Inc. (ADAG) market action, institutional positioning, and fundamental catalysts.
ADAG Bull vs. Bear Conversation Board — What's Your Call at $2.29?
Debt/Equity of 0.03 and $74.5M in reported cash give the balance sheet meaningful liquidity against a low leverage profile.
Here is why I am bullish on ADAG here at $2.51: Debt/Equity of 0.03 and $74.5M in reported cash give the balance sheet meaningful liquidity against a low leverage profile.. Compare ADAG's -60.0% operating margin and -35.0% ROIC against the rest of Biotechnology: Pharmaceutical Preparations. As long as cash conversion holds up, dips toward $2.38 are getting bought.
Both sides have a point here — ADAG's 8/20 balance sheet score keeps downside contained, so the real swing factor next earnings call is backlog and FCF conversion.
Negative ROIC of -35%, FCF of -$15.7M, and an Altman Z-Score of 0.2 show the company is consuming capital with distress-level forensic
I respect the product at Adagene Inc., but the stock at $2.51 is a different story. Negative ROIC of -35%, FCF of -$15.7M, and an Altman Z-Score of 0.2 show the company is consuming capital with distress-level forensic readings.. FCF yield is -8.85% and RQD sits at 25/100 (E) — why pay up here when you can wait for next quarter's numbers?