StockInvest.us report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Why BCYC Stock dropped -4.19% Today — RQD Quant Desk Flash
Bicycle Therapeutics plc (BCYC) carries a Roarable Rating of E (Strong Sell) with 20/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief)
Is BCYC stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-03, Bicycle Therapeutics plc (NASDAQ: BCYC) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 20/100 at a spot price of $3.66 (-4.19% 1D, market cap $256.5M). Pillar breakdown: Fundamental Cash Engine 3/20, Institutional 13F & Options Flow 5/20, Executive Insider Alignment 5/20, FRED Macro Regime Fit 5/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, BCYC ranks #979 in composite RQD confidence.
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief)
How does BCYC compare to LRMR and GLSI in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), BCYC carries a Roarable E (20/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, LRMR (Larimar Therapeutics Inc.) holds a E grade (34/100 RQD, P/E N/A, ROIC -35.0%, cap $256.6M) and GLSI (Greenwich LifeSciences Inc.) posts a E grade (31/100 RQD, P/E N/A, ROIC -35.0%, cap $255.5M). Among the 5-stock peer group, BCYC leads on earnings multiple (N/A) while AMRN leads on capital efficiency (-12.2% ROIC).
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief)
What are the biggest fundamental strengths and SEC risk factors for BCYC?
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Per BCYC's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001761612), Bicycle Therapeutics plc generated $72.6M in revenue (+105.8% YoY), -$219.0M in net income, and -$252.0M in free cash flow against $717.6M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
20D Institutional Volume Accumulation (±11.4% realized swing band)
Altman Z-Score 0.20 (DISTRESS RISK (<1.8)) • Piotroski F-Score 2/9
Dilution Drag (+1.28% YoY Shares) & executive Form 4 sales trim 16 pts from alignment
⚔️ Adversarial Opposing Case: What Could Spark a BCYC Turnaround Squeeze
While BCYC currently carries a cautious 20/100 (E) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
Established market leader in Health Care with deep daily trading liquidity.
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($3.81) and Max Pain ($3.84) forces dealer call-delta covering toward $8.52.
Forensic Repair Trigger: Halting share dilution (Dilution Drag (+1.28% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
Why BCYC Stock dropped -4.19% Today — RQD Quant Desk Flash
Bicycle Therapeutics plc (BCYC) dropped -4.19% to $3.66, trading at 7% of its 52-week range ($3.33 – $8.11). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 7% of its 52-week range ($3.33 – $8.11) with RSI-14 at 48.1 (NEUTRAL RANGE).
- ▸Volatility Profile: Historical 20-day realized swing band of ±11.4% around $3.66 (no active unusual options sweep snapshot on file).
- ▸Fundamental Anchor: Roarable E (Strong Sell) backed by 52% gross margin and $0 annual free cash flow.
Yahoo Finance UK report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Simply Wall St report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Kalkine report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Quiver Quantitative report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
CAMBRIDGE, England & BOSTON, October 29, 2026--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycl
Bicycle Therapeutics (NASDAQ:BCYC) reported quarterly losses of $(0.15) per share which beat the analyst consensus estimate of $(0.48) by 68.75 percent. This is a 82.35 percent increase over losses of $(0.85) per share
Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring BCYC)
- ✓Walkthrough of BCYC's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
- ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
BCYC Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. +105.8% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on BCYC today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for BCYC. Explore sector supply chains on /butterfly.
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (BCYC)
1. Head-to-Head Health Care Peer Comparison (BCYC vs. LRMR, GLSI, AMRN, ABEO)
Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)Across 1016 tracked Health Care securities in the Roarable RQD universe, Bicycle Therapeutics plc (BCYC) ranks #979 by composite RQD confidence (20/100, grade E) and #536 by equity capitalization ($256.5M). Within this direct 5-issuer industry benchmark cohort, BCYC leads on earnings valuation at N/A trailing P/E, while AMRN leads on capital efficiency and profitability with -12.2% ROIC and 56.6% gross margin. LRMR currently holds the highest overall quantitative score in the immediate peer group at 34/100 (E) compared with BCYC at 20/100 (E).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| BCYC
ACTIVE
Bicycle Therapeutics plc | E | 20/100 | — | — | -35.0% | -4.19% | $256.5M | Benchmark Subject |
| LRMR Larimar Therapeutics Inc. | E | 34/100 | — | — | -35.0% | -7.49% | $256.6M | /lrmr-vs-bcyc → |
| GLSI Greenwich LifeSciences Inc. | E | 31/100 | — | — | -35.0% | -8.37% | $255.5M | /glsi-vs-bcyc → |
| AMRN Amarin Corporation plc | E | 32/100 | — | 56.6% | -12.2% | -4.91% | $249.9M | /amrn-vs-bcyc → |
| ABEO Abeona Therapeutics Inc. | E | 23/100 | — | 73.7% | -35.0% | -4.61% | $248.8M | /abeo-vs-bcyc → |
2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)
SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001761612In its most recent audited fiscal period (FY2025, filed 2025-12-31), Bicycle Therapeutics plc (BCYC) reported GAAP revenue of $72.6M (+105.8% vs. FY2024 revenue of $35.3M , and +169.1% cumulative change since FY2023) , GAAP net income of -$219.0M, operating cash flow of -$249.7M, and free cash flow of -$252.0M (-51.9% YoY). On the balance sheet, BCYC closed FY2025 with $717.6M in total assets against $0 in total debt (Altman Z-Score: 0.20, Piotroski F-Score: 2/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $72.6M | -$219.0M | -$249.7M | -$252.0M | $717.6M | — |
| FY2024 (FY) | 2024-12-31 | $35.3M | -$169.0M | -$164.7M | -$166.0M | $956.9M | — |
| FY2023 (FY) | 2023-12-31 | $27.0M | -$180.7M | -$60.6M | -$60.6M | — | — |
3. BCYC Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs BCYC stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-03, Bicycle Therapeutics plc (NASDAQ: BCYC) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 20/100 at a spot price of $3.66 (-4.19% 1D, market cap $256.5M). Pillar breakdown: Fundamental Cash Engine 3/20, Institutional 13F & Options Flow 5/20, Executive Insider Alignment 5/20, FRED Macro Regime Fit 5/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, BCYC ranks #979 in composite RQD confidence.
How does BCYC compare to LRMR and GLSI in the Health Care sector?
Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), BCYC carries a Roarable E (20/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, LRMR (Larimar Therapeutics Inc.) holds a E grade (34/100 RQD, P/E N/A, ROIC -35.0%, cap $256.6M) and GLSI (Greenwich LifeSciences Inc.) posts a E grade (31/100 RQD, P/E N/A, ROIC -35.0%, cap $255.5M). Among the 5-stock peer group, BCYC leads on earnings multiple (N/A) while AMRN leads on capital efficiency (-12.2% ROIC).
What are the biggest fundamental strengths and SEC risk factors for BCYC?
Per BCYC's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001761612), Bicycle Therapeutics plc generated $72.6M in revenue (+105.8% YoY), -$219.0M in net income, and -$252.0M in free cash flow against $717.6M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
Where is BCYC trading relative to its 50-day, 200-day, and 52-week technical levels?
BCYC last traded at $3.66 (-4.19% on volume of 348,594 shares), positioning the stock -3.94% below its 50-day simple moving average ($3.81) and -19.38% below its 200-day simple moving average ($4.54). Across its 52-week range of $3.33 to $8.11, BCYC sits at the 6.9% percentile with a 14-day RSI of 48.1 (NEUTRAL RANGE) and an implied next-earnings move of ±11.4% ($3.24 to $4.08).
BCYC Investor FAQ & Complete 8-Part Research Index
100% OPEN ACCESS • SEC EDGAR × CBOE × FREDWhy is BCYC stock moving today?
Why BCYC Stock dropped -4.19% Today — RQD Quant Desk Flash. Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
BCYC — Bicycle Therapeutics plc: What the Facts Mean to a Prospective Investor
Roarable Rating Brief: What This Means to a Prospective Investor
Per the Roarable RQD rating, BCYC carries an RQD Score of 21 and a letter grade of E, with the verdict "Roarable Strong Sell — Forensic Risk / Avoid." Across the five pillars, the fundamental cash engine scores 2 of 20 (ROIC -35%; FCF yield 0%), indicating the business is not currently generating returns on capital or free cash flow. Whale/13F flow scores 6 of 20 for institutional accumulation and options positioning, the second-weakest pillar after fundamentals. Insider conviction scores 3 of 20 based on SEC Form 4 and Congressional PTR cluster flow. Macro regime fit scores 5 of 20 with a beta of 1.0 and noted sector sensitivity. Forensic balance sheet scores 5 of 20, reflecting an Altman Z of 0.2, a Piotroski F of 2/9, and a Debt/Equity of 0.5.
For a prospective investor evaluating the stock today, these pillars point to a profile where the primary upside case would have to rest on a future inflection rather than current economics. The price of 3.82 sits within a 52-week range of $3.33 to $8.48, and the market cap of $267.4M is small relative to the reported operating loss of $-247.1M in FY 2025. Valuation multiples such as P/E and EV/EBITDA are not available in source data, so relative valuation cannot be assessed from these sources. The weak forensic and insider readings mean the score offers little independent confirmation of an upside thesis. Any investment case would depend on information outside this dataset.
Recent Catalysts & News Wire Analysis
Per the recent news feed, the items cover several themes:
- Analyst target action (RED / RISK WATCH): A TradingView report references a 12-month price target cut to $9.86, which it frames as implying 154% upside.
- Insider transaction (YELLOW / MARKET WIRE): A Stock Titan report describes a director selling 3,431 shares to cover vesting taxes.
- Strategic pivot (RED / RISK WATCH): A Kalkine report describes a narrowed net loss and a pipeline pivot toward radioligand therapies in Q3 2026.
- Positive catalyst (GREEN / CATALYST): A Simply Wall St report, titled around driving business growth carefully, is tagged as a catalyst.
- General market coverage (YELLOW / MARKET WIRE): StockInvest.us and Yahoo Finance UK items cover market action and seasonal returns without specific new facts.
The Butterfly Supply-Chain Graph reports supply_chain as NONE, with no butterfly links and no proprietary signals.
Open Questions
- What are BCYC's products, clinical programs, and revenue sources, given that the source data describes only the sector and industry?
- What drove the FY 2025 revenue increase to $72.6M, and what portion is recurring versus one-time?
- What is the current cash runway given cash of $628.1M against an FY 2025 FCF of $-252.0M, and what is the stated debt position?
- What are the terms and timing of the reported pipeline pivot toward radioligand therapies?
- What institutional, insider, and analyst positioning exists, since the holders and analyst sections are empty?
BCYC Live News Feed, Press Releases & Catalyst Wire
Real-time company headlines, analyst actions, and sector developments for Bicycle Therapeutics plc (BCYC) • Click "Debate This Headline" to argue it in the Roar Pit below
StockInvest.us report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Yahoo Finance UK report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Simply Wall St report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Kalkine report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Quiver Quantitative report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Bicycle Therapeutics plc (BCYC) market action, institutional positioning, and fundamental catalysts.
BCYC Bull vs. Bear Conversation Board — What's Your Call at $3.66?
🔥 Official Bull vs. Bear Debate: Is BCYC (E • RQD 21/100) a Buy at $3.82?
Welcome to the BCYC (Bicycle Therapeutics plc) Roar Pit. Current RQD Composite is 21/100 (Roarable Strong Sell — Forensic Risk / Avoid) in Biotechnology: Pharmaceutical Preparations. Bulls point to operating leverage and sector positioning, while bears focus on macro rate sensitivity and margin execution. Pick your side (🐂 Bull or 🐻 Bear) and drop your price target below.
Pump the brakes on BCYC — check the valuation vs. margin headwinds
Everyone in here is repeating the bull case on BCYC, but look at what you are paying: current EV/EBITDA multiples with tightening sector spreads. Unless Bicycle Therapeutics plc expands free cash flow yield next quarter, I would rather wait for a pullback closer to the 200-day moving average before touching this.
BCYC cash flow & RQD setup is being underpriced by the Street here
Looking at the 5-pillar RQD breakdown on BCYC, the market is fixating on short-term headline noise in Biotechnology: Pharmaceutical Preparations and ignoring the balance sheet and cash flow trajectory. At $3.82 (52-wk range $3.33 - $8.48), any beat on forward guidance forces shorts and underweight funds to chase.