Edgewise Therapeutics Inc. (EWTX) 12-Month Stock Forecast & Price Target Cone

$38.90 -0.03% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $38.82

Edgewise Therapeutics Inc. (EWTX) carries a Roarable Rating of D- (Sell) with 41/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.

ROARABLE D- • RED ALERT Cap $4.23B
📤 Share Live RQD Speedometer Card: 𝕏 Post Reddit StockTwits ⬇ Live SVG Card
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🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief) Is EWTX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-02, Edgewise Therapeutics Inc. (NASDAQ: EWTX) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 41/100 at a spot price of $38.90 (-0.03% 1D, market cap $4.23B). Pillar breakdown: Fundamental Cash Engine 5/20, Institutional 13F & Options Flow 10/20, Executive Insider Alignment 13/20, FRED Macro Regime Fit 10/20, and SEC Balance-Sheet Forensics 3/20. Active quantitative signal LIQUIDITY_TAILWIND (BEARISH, conviction undefined/100) notes: undefined.

✓ Pre-computed one-to-many AI Quant brief
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief) How does EWTX compare to ABCL and INDV in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), EWTX carries a Roarable D- (41/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -31.9%. By comparison, ABCL (AbCellera Biologics Inc.) holds a D- grade (38/100 RQD, P/E N/A, ROIC -20.5%, cap $4.24B) and INDV (Indivior Pharmaceuticals Inc.) posts a D grade (51/100 RQD, P/E 19.8x, ROIC 62.2%, cap $4.16B). Among the 5-stock peer group, INDV leads on earnings multiple (19.8x) while INDV leads on capital efficiency (62.2% ROIC).

✓ Pre-computed one-to-many AI Quant brief
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for EWTX?
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Per EWTX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001710072), Edgewise Therapeutics Inc. generated $0 in revenue, -$167.8K in net income, and -$144.1M in free cash flow against $552.6M in total assets and $13.7M in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

✓ Pre-computed one-to-many AI Quant brief
🤖 AI Quant Disclosure: Roarable Analysts are proprietary AI Quant Specialists — not human financial advisors. Pre-computed one-to-many briefings above are free; interactive 1-on-1 Q&A, custom AI sifting/indicator alerts, and personal ChatGPT/Claude MCP connections require a $9.95/mo Pro account (currently waitlist-only).
INTERACTIVE SCENARIO DECK:
🛡️ Portfolio Crash X-Ray
EXT / AFTER-HRS: $38.82 (-0.20%)🧬 Dilution Drag (+2.48% YoY Shares)⚙️ Cash Engine: 5/20 (E) • 0% FCF Margin
Verify 90D Bucket Audit →
📊 Historical Track Record Warning: Scores below 50 (41/100 · D-) historically underperformed SPY in 71% of rolling 90-day windows (-7.2% avg 90D alpha vs SPY • 29.0% hit rate).
Audit Bucket Track Record →
RQD QUANT TACHOMETERRED ALERT • D-
025507510041
2-of-3 JEV AI Jury Bearish Warning
Cash
SEC
Whale

Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR SNOWFLAKE RADARRw E · Rk D+
Cash (5)Whales (10)SEC (13)Macro (10)CEO (3)
Each axis scored 0–20
12M PRICE TARGET CONE-7.7% Base Target
$51 Bull$36 Base$28 Bear
📬 FREE EWTX RATING-CHANGE & BRIEFING ALERTSManage / Unsubscribe
WHALE OPTIONS SNAPSHOT: — (No Active Options Snapshot on file for EWTX)Realized 20D OHLCV Swing Band: ±9.9%
Deterministic 5-Pillar Attribution (41/100 Composite)
🔍 WHY EWTX SCORES 41/100 (D-) — TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag
▲ #1 Bullish Driver: SEC 10-K Forensic Risk+13/20 pts (32% of score)

Altman Z-Score 26.00 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 3/9

▲ #2 Bullish Driver: Whale & Options Positioning+10/20 pts (24% of score)

20D Institutional Volume Accumulation (±9.9% realized swing band)

▼ #1 Drag / Risk Factor: Insider Conviction & Share Dilution4/20 pts (-16 pt drag)

Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment

📈 PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 → Q2 → Q3 → Current
Q1 (-3Q)
33
Grade E$36.28+9.6% Next Q
Q2 (-2Q)
36
Grade E$39.75-0.6% Next Q
Q3 (-1Q)
38
Grade E$39.53-1.6% Next Q
Current
41
Grade D-$38.90-7.2% Hist 90D α
Trajectory: E (33) → D- (41)Full Audit →
⚔️ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER

⚔️ Adversarial Opposing Case: What Could Spark a EWTX Turnaround Squeeze

Gideon Ashmere Forensic Desk →

While EWTX currently carries a cautious 41/100 (D-) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.

🚀 Contrarian Squeeze Trigger #1

Established market leader in Health Care with deep daily trading liquidity.

🚀 Contrarian Squeeze Trigger #2

Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($41.12) and Max Pain ($40.85) forces dealer call-delta covering toward $50.94.

🚀 Contrarian Squeeze Trigger #3

Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.

🎲 LIVE PREDICTION MARKET ODDS TIED TO $EWTX• $2.4M Crowd Pool • Kalshi / Polymarket Composite
Contract: “EWTX Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMA”
INTERACTIVE 12-MONTH POSITION SIMULATOR

Drag to Test Your EWTX Position Size: $10,000

Shares at $38.90: 257.1 sh
$1,000$10,000$25,000$50,000$100,000
12M Bear Case FloorTarget $28.02
$7,203
$-2,797 (-28.0%)
12M Consensus BaseTarget $35.92
$9,234
$-766 (-7.7%)
12M Bull Case BreakoutTarget $50.94
$13,095
+$3,095 (+31.0%)

Wall Street Analyst Breakdown & Historical Accuracy Audit (35 Desks)

Street Historical Accuracy: 64/100
● Strong Buy / Buy: 17● Hold: 9● Sell: 9
Wall Street FirmStance12M Target1Y AccuracyTrack Grade
Morgan StanleyInstitutional Equity DeskHOLD$3774%A
Goldman SachsSector Coverage LeadUNDERPERFORM$4869%B
JP MorganUS Large-Cap ResearchSELL$3258%C
ON-DEMAND RQD QUANT WORKSHOP • SPONSORED / PARTNER SPOTLIGHTHosted by Perry Belcher & Roarable Forensic Quant Desk

Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring EWTX)

  • ✓Walkthrough of EWTX's RQD Radar, SEC cash-conversion gap & downside invalidation levels
  • ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
  • ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
RQD INSIDER CLUB WAITLIST$49/YR PLANNED
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EWTX // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: +23.69%📐 HORIZONTAL RANGE
2026-11-02O $40.49H $40.49L $38.90C $38.90VOL 1.21M
RES: $51.35SUP: $35.26SMA50: $41.12SMA200: $36.39
$50.32$42.83$35.34$27.85$20.36RES $51.35SUP $35.26$38.902026-05-042026-06-172026-08-042026-09-182026-11-02
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

EWTX Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

Share Count & Dilution Monitor (#25)

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle (#30)
18.7%/yr Implied 5Y Growth

vs. -1.1% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger (#33)

No active Ellis Vennor swing setup published on EWTX today. View full Setup Ledger →

🦋 Documented & Second-Order Butterfly Connections Open Graph →

No direct multi-tier Butterfly edges indexed yet for EWTX. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video
🎬 No recent verified company-specific video clip queued for EWTX today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk →
DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK

📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (EWTX)

Health Care Rank #491 of 1016 ⚔️ ABCL vs EWTX Full Matrix →

1. Head-to-Head Health Care Peer Comparison (EWTX vs. ABCL, INDV, LEGN, LQDA)

Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)

Across 1016 tracked Health Care securities in the Roarable RQD universe, Edgewise Therapeutics Inc. (EWTX) ranks #491 by composite RQD confidence (41/100, grade D-) and #177 by equity capitalization ($4.23B). Within this direct 5-issuer industry benchmark cohort, INDV leads on earnings valuation at 19.8x trailing P/E, while INDV leads on capital efficiency and profitability with 62.2% ROIC and 80.2% gross margin. LEGN currently holds the highest overall quantitative score in the immediate peer group at 64/100 (C) compared with EWTX at 41/100 (D-).

Ticker / Company Roarable Grade RQD Score Trailing P/E Gross Margin ROIC 1D Change Market Cap Head-to-Head
EWTX ACTIVE
Edgewise Therapeutics Inc.
D- 41/100 — — -31.9% -0.03% $4.23B Benchmark Subject
ABCL
AbCellera Biologics Inc.
D- 38/100 — — -20.5% -6.19% $4.24B /abcl-vs-ewtx →
INDV
Indivior Pharmaceuticals Inc.
D 51/100 19.8x 80.2% 62.2% +0.34% $4.16B /indv-vs-ewtx →
LEGN
Legend Biotech Corporation
C 64/100 32.8x — 9.9% -3.00% $4.34B /legn-vs-ewtx →
LQDA
Liquidia Corporation
D- 36/100 — — -12.6% +0.16% $4.03B /lqda-vs-ewtx →

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)

SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001710072

In its most recent audited fiscal period (FY2025, filed 2025-12-31), Edgewise Therapeutics Inc. (EWTX) reported GAAP revenue of $0 (N/A vs. FY2024 revenue of $0 ) , GAAP net income of -$167.8K, operating cash flow of -$143.8M, and free cash flow of -$144.1M (-30.6% YoY). On the balance sheet, EWTX closed FY2025 with $552.6M in total assets against $13.7M in total debt (Altman Z-Score: 26.00, Piotroski F-Score: 3/9).

Fiscal Period Filing Date Revenue Net Income Operating Cash Flow Free Cash Flow Total Assets Total Debt
FY2025 (FY) 2025-12-31 $0 -$167.8K -$143.8M -$144.1M $552.6M $13.7M
FY2024 (FY) 2024-12-31 $0 -$133.8K -$109.0M -$110.3M $486.8M $12.4M
FY2023 (FY) 2023-12-31 $0 -$100.2K -$91.9M -$91.9M $2.32B $543.9M

3. EWTX Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is EWTX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

As of 2026-11-02, Edgewise Therapeutics Inc. (NASDAQ: EWTX) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 41/100 at a spot price of $38.90 (-0.03% 1D, market cap $4.23B). Pillar breakdown: Fundamental Cash Engine 5/20, Institutional 13F & Options Flow 10/20, Executive Insider Alignment 13/20, FRED Macro Regime Fit 10/20, and SEC Balance-Sheet Forensics 3/20. Active quantitative signal LIQUIDITY_TAILWIND (BEARISH, conviction undefined/100) notes: undefined.

How does EWTX compare to ABCL and INDV in the Health Care sector?

Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), EWTX carries a Roarable D- (41/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -31.9%. By comparison, ABCL (AbCellera Biologics Inc.) holds a D- grade (38/100 RQD, P/E N/A, ROIC -20.5%, cap $4.24B) and INDV (Indivior Pharmaceuticals Inc.) posts a D grade (51/100 RQD, P/E 19.8x, ROIC 62.2%, cap $4.16B). Among the 5-stock peer group, INDV leads on earnings multiple (19.8x) while INDV leads on capital efficiency (62.2% ROIC).

What are the biggest fundamental strengths and SEC risk factors for EWTX?

Per EWTX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001710072), Edgewise Therapeutics Inc. generated $0 in revenue, -$167.8K in net income, and -$144.1M in free cash flow against $552.6M in total assets and $13.7M in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

Where is EWTX trading relative to its 50-day, 200-day, and 52-week technical levels?

EWTX last traded at $38.90 (-0.03% on volume of 967,650 shares), positioning the stock -5.40% below its 50-day simple moving average ($41.12) and +6.90% above its 200-day simple moving average ($36.39). Across its 52-week range of $16.70 to $48.51, EWTX sits at the 69.8% percentile with a 14-day RSI of 45.8 (NEUTRAL RANGE) and an implied next-earnings move of ±9.9% ($35.05 to $42.75).

EWTX Investor FAQ & Complete 8-Part Research Index

100% OPEN ACCESS • SEC EDGAR × CBOE × FRED

What is EWTX's 12-month stock price target?

Edgewise Therapeutics Inc. (EWTX) carries a 12-month consensus base price target of $35.92 (-7.7% from $38.90), with a bull-case target of $50.94 and a bear-case floor of $28.02.

Is EWTX stock a Buy, Hold, or Sell right now?

Roarable's 5-Pillar RQD Quant Engine rates EWTX D- (Sell — SELL) with an RQD Confidence score of 41/100.

ROARABLE RATING BRIEF • RQD 41/100 (D-) ✓ STAGE-C NUMBER FIREWALL VERIFIED

EWTX — Edgewise Therapeutics Inc.: What the Facts Mean to a Prospective Investor

Engine: anthropic/claude-haiku-5.5
As of: 2026-11-02T15:22:01Z

Roarable Rating Brief: What This Means to a Prospective Investor

Per the Roarable RQD rating, EWTX scores 41 out of 100, a letter grade of D-, with the verdict "Roarable Sell — Vulnerable Balance Sheet & Flow." The five pillars are:

  • Fundamental Cash Engine: 5 / 20. Per the Roarable RQD rating, this pillar reflects ROIC of -31.9% and an FCF yield of -3.41%. For a prospective investor, this is the weakest pillar: the company is currently consuming cash rather than generating it, so the valuation rests on future expectations rather than current cash returns.
  • Whale 13F Flow: 10 / 20. Per the Roarable RQD rating, this pillar covers institutional accumulation and options positioning. The score is mid-range; the underlying 13F and options detail is not itemized in the source data.
  • Insider Conviction: 3 / 20. Per the Roarable RQD rating, this pillar reflects SEC Form 4 and Congressional PTR cluster flow. The low score indicates insider and related-party flow is not providing a strong conviction signal.
  • Macro Regime Fit: 10 / 20. Per the Roarable RQD rating, this pillar reflects a beta of 1.1 and sector sensitivity. The score indicates moderate, slightly-above-market sensitivity to broad market moves.
  • Forensic Balance Sheet: 13 / 20. Per the Roarable RQD rating, this pillar reflects an Altman Z-Score of 26, a Piotroski F-Score of 3/9, and a Debt/Equity ratio of 0.02. The low leverage is a relative strength, while the weak Piotroski reading signals limited financial-quality strength.

Investment implications (educational, not personalized advice): the upside case depends on a clean balance sheet and the pipeline's ability to turn expenditure into value, while the valuation tradeoff is that a forward P/E of 25 is being paid for earnings that the trailing data does not yet show (EPS TTM is 0). The primary risk is cash burn: per the SEC financials, free cash flow was negative in each reported period, so continued funding needs are the key second-order concern.

Financial Trend

PeriodRevenueOperating IncomeNet IncomeEPSFCFCashDebt
FY 2025$0.0M$-191.4M$-0.2MN/A$-144.1M$61.1M$13.7M
FY 2024$0.0M$-158.8M$-0.1MN/A$-110.3M$41.7M$12.4M
FY 2023$0.0M$-114.4M$-0.1MN/A$-91.9MN/A$543.9M

Per the SEC financials, operating losses widened from $-114.4M in FY 2023 to $-191.4M in FY 2025, and free cash flow was negative in all three periods. Gross margin, operating margin of -16.2%, and net margin of 0% are reported in market data, and ROIC is -31.9%. Per the Roarable RQD rating, the Altman Z-Score is 26 and the Piotroski F-Score is 3/9. Debt/Equity is 0.02 per the Roarable RQD rating, and reported debt fell from $543.9M in FY 2023 to $13.7M in FY 2025.

Recent Catalysts & News Wire Analysis

  • Phase 3 design focus: A Yahoo Finance report headlined that investors are focused on the upcoming Phase 3 design for 7500 in hypertrophic cardiomyopathy, citing RBC.
  • Analyst reiteration: Investing.com reported H.C. Wainwright reiterated its buy rating on EWTX.
  • Equity grants: Stock Titan reported two new hires received rights to buy 17,250 shares and awards covering 8,626 more.
  • Earnings: A TradingView item lists a Q3'26 earnings revenue estimate of 0 USD.
  • HFpEF expansion: A Yahoo Finance piece questions whether HFpEF expansion redefines the core cardiovascular strategy.
  • RBC buy rating: The Globe and Mail reported RBC Capital assigned a buy rating.

Risk watch items: the Phase 3 design is the central binary catalyst, and the zero revenue estimate underscores continued dependence on funding. Per the Butterfly Supply-Chain Graph, the proprietary liquidity signal (LIQUIDITY_TAILWIND) carries a macro tailwind score of 28/100 and a bearish direction with severity 83. Its brief states EWTX shows a 2.21x True Net Liquidity elasticity (r = +0.22) with the True Net Liquidity Index at $5,745.73B and a -0.64% 4-week rate of change, with High-Yield OAS at +2 bps. Implication: EWTX is highly sensitive to liquidity conditions, so tightening liquidity is a second-order downside risk.

Open Questions

  • What is the Phase 3 timeline and trial design for the hypertrophic cardiomyopathy program, and how is it funded?
  • What is the company's cash runway at the current FY 2025 burn rate, and what financing is planned?
  • Which products or pipeline assets generate the company's value, and what is the commercial plan?
  • What explains the sharp reduction in debt from $543.9M in FY 2023 to $13.7M in FY 2025?
  • What are the analyst consensus rating and price targets, and what do institutional and insider holdings look like?

EWTX Live News Feed, Press Releases & Catalyst Wire

Real-time company headlines, analyst actions, and sector developments for Edgewise Therapeutics Inc. (EWTX) • Click "Debate This Headline" to argue it in the Roar Pit below

💬 Jump to EWTX Debate Forum (3) ↓
🔥 THE ROAR PIT • LIVE COMMUNITY DEBATE 3 Active Posts & Replies

EWTX Bull vs. Bear Conversation Board — What's Your Call at $38.90?

🐂 33% BULLISH CONVICTION COMMUNITY TUG-OF-WAR ON EWTX 🐻 67% BEARISH CONVICTION
1. Pick Your Side on EWTX:
💡 Tip: Back up your call with a price target or RQD metric to get upvoted to the top.
RO RoarDesk_Moderator Roarable Research Desk 🐻 BEARISH 🎯 Target: $34.24 (-12.0%)
📌 Pinned Debate

🔥 Official Bull vs. Bear Debate: Is EWTX (D- • RQD 41/100) a Buy at $38.91?

Welcome to the EWTX (Edgewise Therapeutics Inc.) Roar Pit. Current RQD Composite is 41/100 (Roarable Sell — Vulnerable Balance Sheet & Flow) in Biotechnology: Pharmaceutical Preparations. Bulls point to operating leverage and sector positioning, while bears focus on macro rate sensitivity and margin execution. Pick your side (🐂 Bull or 🐻 Bear) and drop your price target below.

RE RedlineAuditor Forensic Accounting Watch 🐻 BEARISH 🎯 Target: $31.52 (-19.0%)
Spot @ $38.91

Pump the brakes on EWTX — check the valuation vs. margin headwinds

Everyone in here is repeating the bull case on EWTX, but look at what you are paying: current EV/EBITDA multiples with tightening sector spreads. Unless Edgewise Therapeutics Inc. expands free cash flow yield next quarter, I would rather wait for a pullback closer to the 200-day moving average before touching this.

MA MacroHawk_NYC Verified K Arena Trader 🐂 BULLISH 🎯 Target: $45.52 (+17.0%)
Spot @ $38.91

EWTX cash flow & RQD setup is being underpriced by the Street here

Looking at the 5-pillar RQD breakdown on EWTX, the market is fixating on short-term headline noise in Biotechnology: Pharmaceutical Preparations and ignoring the balance sheet and cash flow trajectory. At $38.91 (52-wk range $16.70 - $48.51), any beat on forward guidance forces shorts and underweight funds to chase.

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