Yahoo Finance report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Why HOWL Stock dropped -10.35% Today — RQD Quant Desk Flash
Werewolf Therapeutics Inc. (HOWL) carries a Roarable Rating of D- (Sell) with 42/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief)
Is HOWL stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-03, Werewolf Therapeutics Inc. (NASDAQ: HOWL) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 42/100 at a spot price of $0.99 (-10.35% 1D, market cap $47.9M). Pillar breakdown: Fundamental Cash Engine 4/20, Institutional 13F & Options Flow 11/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 12/20, and Executive Insider Alignment 5/20. Across 1015 tracked Health Care issuers, HOWL ranks #428 in composite RQD confidence.
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief)
How does HOWL compare to ANVS and SER in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), HOWL carries a Roarable D- (42/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, ANVS (Annovis Bio Inc.) holds a D- grade (35/100 RQD, P/E N/A, ROIC -35.0%, cap $48.2M) and SER (Serina Therapeutics Inc.) posts a E grade (31/100 RQD, P/E N/A, ROIC -35.0%, cap $49.3M). Among the 5-stock peer group, HOWL leads on earnings multiple (N/A) while HOWL leads on capital efficiency (-35.0% ROIC).
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief)
What are the biggest fundamental strengths and SEC risk factors for HOWL?
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Per HOWL's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001785530), Werewolf Therapeutics Inc. generated $169.9M in revenue (-17.6% YoY), -$60.8M in net income, and -$60.3M in free cash flow against $69.4M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
FRED Regime × Technicals: 68% of 52W Range • RSI-14 at 51.2 (NEUTRAL RANGE)
20D Institutional Volume Accumulation (±12.5% realized swing band)
Capital intensity & 0% operating margin leave 16 pts on the table
⚔️ Adversarial Opposing Case: What Could Spark a HOWL Turnaround Squeeze
While HOWL currently carries a cautious 42/100 (D-) rating due to Cash Engine Quality (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
Established market leader in Health Care with deep daily trading liquidity.
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($0.97) and Max Pain ($1.04) forces dealer call-delta covering toward $1.40.
Forensic Repair Trigger: Halting share dilution (Disciplined Float (+0.72% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
Why HOWL Stock dropped -10.35% Today — RQD Quant Desk Flash
Werewolf Therapeutics Inc. (HOWL) dropped -10.35% to $0.99, trading at 68% of its 52-week range ($0.27 – $1.33). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 68% of its 52-week range ($0.27 – $1.33) with RSI-14 at 51.2 (NEUTRAL RANGE).
- ▸Volatility Profile: Historical 20-day realized swing band of ±12.5% around $0.99 (no active unusual options sweep snapshot on file).
- ▸Fundamental Anchor: Roarable D- (Sell) backed by 52% gross margin and $0 annual free cash flow.
TradingView report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Yahoo Finance report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Simply Wall St report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Syfe report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Yahoo Finance report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Werewolf Therapeutics, Inc. (the "Company" or "Werewolf") (NASDAQ:HOWL), an innovative biopharmaceutical company pioneering the development of conditionally activated therapeutics engineered to stimulate
Gainers Neumora Therapeutics (NASDAQ:NMRA) shares rose 11.9% to $0.41 during Tuesday's after-market session. The market value of their outstanding shares is at $73.8 million. Pulmonx (NASDAQ:LUNG) stock increased
Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring HOWL)
- ✓Walkthrough of HOWL's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
- ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
HOWL Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. -17.6% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on HOWL today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for HOWL. Explore sector supply chains on /butterfly.
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (HOWL)
1. Head-to-Head Health Care Peer Comparison (HOWL vs. ANVS, SER, GANX, ATNM)
Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)Across 1015 tracked Health Care securities in the Roarable RQD universe, Werewolf Therapeutics Inc. (HOWL) ranks #428 by composite RQD confidence (42/100, grade D-) and #752 by equity capitalization ($47.9M). Within this direct 5-issuer industry benchmark cohort, HOWL leads on earnings valuation at N/A trailing P/E, while HOWL leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. ATNM currently holds the highest overall quantitative score in the immediate peer group at 43/100 (D-) compared with HOWL at 42/100 (D-).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| HOWL
ACTIVE
Werewolf Therapeutics Inc. | D- | 42/100 | — | — | -35.0% | -10.35% | $47.9M | Benchmark Subject |
| ANVS Annovis Bio Inc. | D- | 35/100 | — | — | -35.0% | +10.78% | $48.2M | /anvs-vs-howl → |
| SER Serina Therapeutics Inc. | E | 31/100 | — | — | -35.0% | +2.65% | $49.3M | /ser-vs-howl → |
| GANX Gain Therapeutics Inc. | D- | 41/100 | — | — | -35.0% | -5.04% | $49.3M | /ganx-vs-howl → |
| ATNM Actinium Pharmaceuticals Inc. (Delaware) | D- | 43/100 | — | — | -35.0% | -3.27% | $46.5M | /atnm-vs-howl → |
2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)
SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001785530 ↗In its most recent audited fiscal period (FY2025, filed 2025-12-31), Werewolf Therapeutics Inc. (HOWL) reported GAAP revenue of $169.9M (-17.6% vs. FY2024 revenue of $206.1M , and +49.8% cumulative change since FY2023) , GAAP net income of -$60.8M, operating cash flow of -$60.3M, and free cash flow of -$60.3M (-6.8% YoY). On the balance sheet, HOWL closed FY2025 with $69.4M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 3/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $169.9M | -$60.8M | -$60.3M | -$60.3M | $69.4M | — |
| FY2024 (FY) | 2024-12-31 | $206.1M | -$70.5M | -$56.2M | -$56.4M | $126.9M | — |
| FY2023 (FY) | 2023-12-31 | $113.4M | -$37.4M | -$32.6M | -$32.6M | — | — |
3. HOWL Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs HOWL stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-03, Werewolf Therapeutics Inc. (NASDAQ: HOWL) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 42/100 at a spot price of $0.99 (-10.35% 1D, market cap $47.9M). Pillar breakdown: Fundamental Cash Engine 4/20, Institutional 13F & Options Flow 11/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 12/20, and Executive Insider Alignment 5/20. Across 1015 tracked Health Care issuers, HOWL ranks #428 in composite RQD confidence.
How does HOWL compare to ANVS and SER in the Health Care sector?
Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), HOWL carries a Roarable D- (42/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, ANVS (Annovis Bio Inc.) holds a D- grade (35/100 RQD, P/E N/A, ROIC -35.0%, cap $48.2M) and SER (Serina Therapeutics Inc.) posts a E grade (31/100 RQD, P/E N/A, ROIC -35.0%, cap $49.3M). Among the 5-stock peer group, HOWL leads on earnings multiple (N/A) while HOWL leads on capital efficiency (-35.0% ROIC).
What are the biggest fundamental strengths and SEC risk factors for HOWL?
Per HOWL's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001785530), Werewolf Therapeutics Inc. generated $169.9M in revenue (-17.6% YoY), -$60.8M in net income, and -$60.3M in free cash flow against $69.4M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Where is HOWL trading relative to its 50-day, 200-day, and 52-week technical levels?
HOWL last traded at $0.99 (-10.35% on volume of 415,566 shares), positioning the stock +2.06% above its 50-day simple moving average ($0.97) and +45.59% above its 200-day simple moving average ($0.68). Across its 52-week range of $0.27 to $1.33, HOWL sits at the 67.9% percentile with a 14-day RSI of 51.2 (NEUTRAL RANGE) and an implied next-earnings move of ±12.5% ($1.00 to $1.11).
HOWL — Werewolf Therapeutics Inc.: What the Facts Mean to a Prospective Investor
1. Roarable Rating Brief: What This Means to a Prospective Investor
Werewolf Therapeutics Inc. (HOWL) earns a live Roarable RQD composite score of 42/100, corresponding to a D- letter grade (Roarable Sell) at a spot price of $0.99 (-10.35% 1D, market capitalization $47.9M).
- Fundamental Cash Engine (4/20): Anchored by return on invested capital (ROIC) of -35.0%, gross margin of —, operating margin of —, and free cash flow yield of —.
- Whale 13F & Options Flow (11/20) + Insider Conviction (5/20): Tracks institutional 13F accumulation, CBOE options call/put positioning, and SEC Form 4 / Congressional PTR filings.
- Macro Regime Fit (12/20) + Forensic Balance Sheet (10/20): Incorporates a 1.00x equity beta, Altman Z-Score of N/A, Piotroski F-Score of 3/9, and Debt/Equity of N/A.
2. Business Model, Unit Margins & SEC Financial Trajectory
Werewolf Therapeutics Inc. Is a NASDAQ-listed issuer in the Health Care sector, within the Biotechnology: Pharmaceutical Preparations industry. The company's reported revenue is — in each of the listed periods, so its revenue model is not evident from the financials provided.
In its latest audited SEC EDGAR 10-K filing for FY2025 (filed 2025-12-31), Werewolf Therapeutics Inc. (HOWL) reported $169.9M in annual revenue (up from $206.1M in FY2024, -17.6% YoY) and -$60.8M in GAAP net income. Over the multi-year SEC filing window from FY2023 ($113.4M revenue, -$37.4M net income) through FY2025, HOWL scaled operating cash flow to -$60.3M and free cash flow to -$60.3M, backed by $69.4M in total assets against $0 in total debt.
3. Institutional Bull vs. Bear Thesis & Valuation Tradeoff
- 🐂 Primary Bull Case (D- • RQD 42/100): Established market leader in Health Care with deep daily trading liquidity. Free cash flow yield of — and institutional whale pillar of 11/20. With Fundamental Cash Engine at 4/20 and Institutional Whale Flow at 11/20, sustained execution supports upside toward the upper end of the $0.27 – $1.33 52-week range.
- 🐻 Primary Bear Case & Valuation Risk: Company executives have done more routine share selling than personal cash buying lately. Investors must weigh current valuation against — operating margins and a 1.00x macro beta.
4. 2nd-Order Butterfly Ripples & Key Questions to Watch
Operating in Biotechnology: Pharmaceutical Preparations (Health Care), HOWL carries a macro regime beta of 1.00 and gross margin of —.
- Key Question #1: Can HOWL sustain or expand its — operating margin and -35.0% ROIC against Biotechnology: Pharmaceutical Preparations peers over the next 4 quarters?
- Key Question #2: Following FY2025 revenue of $169.9M and free cash flow of -$60.3M, how will capital allocation balance growth reinvestment against $0 in total debt?
- Key Question #3: How sensitive is HOWL's equity valuation to Health Care capital spending cycles and macro interest-rate shifts (Beta 1.00x)?
HOWL Live News Feed, Press Releases & Catalyst Wire
Real-time company headlines, analyst actions, and sector developments for Werewolf Therapeutics Inc. (HOWL) • Click "Debate This Headline" to argue it in the Roar Pit below
Yahoo Finance report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Yahoo Finance report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Simply Wall St report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Syfe report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
Yahoo Finance report covering Werewolf Therapeutics Inc. (HOWL) market action, institutional positioning, and fundamental catalysts.
HOWL Bull vs. Bear Conversation Board — What's Your Call at $0.99?
A GREEN-flagged upgrade headline to Strong Buy and a 2.5 Altman Z-Score point to institutional interest and a balance sheet that has no
Long HOWL at $0.99 targeting $1.19. A GREEN-flagged upgrade headline to Strong Buy and a 2.5 Altman Z-Score point to institutional interest and a balance sheet that has not yet deteriorated to distress levels.. Institutional whale score is 11/20 and the risk/reward vs. the $0.27 52-week low is skewed heavily in favor of bulls.
@CreditSpread_Watch Fair point on current EV/EBITDA multiples, but you're ignoring the forward operating leverage in Biotechnology: Pharmaceutical Preparations. If gross margin (0.0%) holds, EPS grows into the multiple faster than bears think.
With zero reported revenue, a -35% ROIC, a 0% FCF yield, and cash falling from $111.0M to $57.0M, the company is consuming capital with
Sitting on the sidelines or leaning short HOWL above $0.99. With zero reported revenue, a -35% ROIC, a 0% FCF yield, and cash falling from $111.0M to $57.0M, the company is consuming capital without a visible path to cash generation.. Until Fundamental Cash Engine (4/20) and FCF yield (0.0%) inflect higher, upside is capped near $1.43.