Stock Titan report covering iSpecimen Inc. (ISPC) market action, institutional positioning, and fundamental catalysts.
Why ISPC Stock advanced +0.82% Today — RQD Quant Desk Flash
iSpecimen Inc. (ISPC) carries a Roarable Rating of E (Strong Sell) with 30/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief)
Is ISPC stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-03, iSpecimen Inc. (NASDAQ: ISPC) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 30/100 at a spot price of $0.83 (+0.82% 1D, market cap $2.1M). Pillar breakdown: Fundamental Cash Engine 9/20, Institutional 13F & Options Flow 3/20, SEC Balance-Sheet Forensics 8/20, FRED Macro Regime Fit 7/20, and Executive Insider Alignment 3/20. Across 1015 tracked Health Care issuers, ISPC ranks #817 in composite RQD confidence.
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief)
How does ISPC compare to BIAF and ONMD in the Health Care sector?
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Within the Health Care sector (Biotechnology: Commercial Physical & Biological Resarch), ISPC carries a Roarable E (30/100 RQD), trailing P/E of N/A, gross margin of 11.2%, and ROIC of -35.0%. By comparison, BIAF (bioAffinity Technologies Inc.) holds a E grade (29/100 RQD, P/E N/A, ROIC -35.0%, cap $3.7M) and ONMD (OneMedNet Corp (Class A)) posts a E grade (26/100 RQD, P/E N/A, ROIC -35.0%, cap $25.4M). Among the 5-stock peer group, NRC leads on earnings multiple (44.8x) while NRC leads on capital efficiency (21.0% ROIC).
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief)
What are the biggest fundamental strengths and SEC risk factors for ISPC?
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Per ISPC's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001558569), iSpecimen Inc. generated $1.9M in revenue (-79.2% YoY), -$10.5M in net income, and -$4.2M in free cash flow against $9.5M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
SEC XBRL FY 2025 (10-K): 0% FCF Margin ($0 FCF) & 11.2% Gross Margin
Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 3/9
Dilution Drag (+1.28% YoY Shares) & executive Form 4 sales trim 16 pts from alignment
⚔️ Adversarial Opposing Case: What Could Spark a ISPC Turnaround Squeeze
While ISPC currently carries a cautious 30/100 (E) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
Established market leader in Health Care with deep daily trading liquidity.
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($1.20) and Max Pain ($0.87) forces dealer call-delta covering toward $34.61.
Forensic Repair Trigger: Halting share dilution (Dilution Drag (+1.28% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
Why ISPC Stock advanced +0.82% Today — RQD Quant Desk Flash
iSpecimen Inc. (ISPC) advanced +0.82% to $0.83, trading at 2% of its 52-week range ($0.75 – $32.96). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 2% of its 52-week range ($0.75 – $32.96) with RSI-14 at 33.9 (NEUTRAL RANGE).
- ▸Volatility Profile: Historical 20-day realized swing band of ±12.5% around $0.83 (no active unusual options sweep snapshot on file).
- ▸Fundamental Anchor: Roarable E (Strong Sell) backed by 11.2% gross margin and $0 annual free cash flow.
Benzinga report covering iSpecimen Inc. (ISPC) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering iSpecimen Inc. (ISPC) market action, institutional positioning, and fundamental catalysts.
https://www.siam.in/ report covering iSpecimen Inc. (ISPC) market action, institutional positioning, and fundamental catalysts.
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Postmarket movers for Oct. 29, 2026: top after-hours gainers included SLGB, BURU and WKHS, while GCTK, LNAI and ATEC led the decliners.
Woburn, Massachusetts--(Newsfile Corp. - October 29, 2026) - iSpecimen Inc. (NASDAQ: ISPC) ("iSpecimen" or the "Company"), a provider of human biospecimens, today announced expanded access to fully consented, prospective
Gainers Biohaven (NYSE:BHVN) shares increased by 39.3% to $16.37 during Thursday's pre-market session. The company's market cap stands at $1.7 billion. Vogenx (NASDAQ:VOGX) stock rose 22.05% to $24.89. The
Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring ISPC)
- ✓Walkthrough of ISPC's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
- ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
ISPC Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. -79.2% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on ISPC today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for ISPC. Explore sector supply chains on /butterfly.
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (ISPC)
1. Head-to-Head Health Care Peer Comparison (ISPC vs. BIAF, ONMD, MXCT, NRC)
Industry: Biotechnology: Commercial Physical & Biological Resarch (12 Tracked Issuers)Across 1015 tracked Health Care securities in the Roarable RQD universe, iSpecimen Inc. (ISPC) ranks #817 by composite RQD confidence (30/100, grade E) and #994 by equity capitalization ($2.1M). Within this direct 5-issuer industry benchmark cohort, NRC leads on earnings valuation at 44.8x trailing P/E, while NRC leads on capital efficiency and profitability with 21.0% ROIC and — gross margin. NRC currently holds the highest overall quantitative score in the immediate peer group at 67/100 (C+) compared with ISPC at 30/100 (E).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| ISPC
ACTIVE
iSpecimen Inc. | E | 30/100 | — | 11.2% | -35.0% | +0.82% | $2.1M | Benchmark Subject |
| BIAF bioAffinity Technologies Inc. | E | 29/100 | — | — | -35.0% | +2.75% | $3.7M | /biaf-vs-ispc → |
| ONMD OneMedNet Corp (Class A) | E | 26/100 | — | -30.0% | -35.0% | +1.42% | $25.4M | /onmd-vs-ispc → |
| MXCT MaxCyte Inc. | E | 34/100 | — | 96.0% | -27.1% | -8.80% | $164.1M | /mxct-vs-ispc → |
| NRC NRC Health | C+ | 67/100 | 44.8x | — | 21.0% | +1.80% | $527.1M | /nrc-vs-ispc → |
2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)
SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001558569 ↗In its most recent audited fiscal period (FY2025, filed 2025-12-31), iSpecimen Inc. (ISPC) reported GAAP revenue of $1.9M (-79.2% vs. FY2024 revenue of $9.3M , and -80.6% cumulative change since FY2023) , GAAP net income of -$10.5M, operating cash flow of -$4.2M, and free cash flow of -$4.2M (+48.9% YoY). On the balance sheet, ISPC closed FY2025 with $9.5M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 3/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $1.9M | -$10.5M | -$4.2M | -$4.2M | $9.5M | — |
| FY2024 (FY) | 2024-12-31 | $9.3M | -$12.5M | -$8.3M | -$8.3M | $9.4M | — |
| FY2023 (FY) | 2023-12-31 | $9.9M | -$11.1M | -$5.8M | -$5.8M | — | — |
3. ISPC Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs ISPC stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-03, iSpecimen Inc. (NASDAQ: ISPC) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 30/100 at a spot price of $0.83 (+0.82% 1D, market cap $2.1M). Pillar breakdown: Fundamental Cash Engine 9/20, Institutional 13F & Options Flow 3/20, SEC Balance-Sheet Forensics 8/20, FRED Macro Regime Fit 7/20, and Executive Insider Alignment 3/20. Across 1015 tracked Health Care issuers, ISPC ranks #817 in composite RQD confidence.
How does ISPC compare to BIAF and ONMD in the Health Care sector?
Within the Health Care sector (Biotechnology: Commercial Physical & Biological Resarch), ISPC carries a Roarable E (30/100 RQD), trailing P/E of N/A, gross margin of 11.2%, and ROIC of -35.0%. By comparison, BIAF (bioAffinity Technologies Inc.) holds a E grade (29/100 RQD, P/E N/A, ROIC -35.0%, cap $3.7M) and ONMD (OneMedNet Corp (Class A)) posts a E grade (26/100 RQD, P/E N/A, ROIC -35.0%, cap $25.4M). Among the 5-stock peer group, NRC leads on earnings multiple (44.8x) while NRC leads on capital efficiency (21.0% ROIC).
What are the biggest fundamental strengths and SEC risk factors for ISPC?
Per ISPC's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001558569), iSpecimen Inc. generated $1.9M in revenue (-79.2% YoY), -$10.5M in net income, and -$4.2M in free cash flow against $9.5M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Where is ISPC trading relative to its 50-day, 200-day, and 52-week technical levels?
ISPC last traded at $0.83 (+0.82% on volume of 108,488 shares), positioning the stock -30.83% below its 50-day simple moving average ($1.20) and -82.38% below its 200-day simple moving average ($4.71). Across its 52-week range of $0.75 to $32.96, ISPC sits at the 0.2% percentile with a 14-day RSI of 33.9 (NEUTRAL RANGE) and an implied next-earnings move of ±12.5% ($1.00 to $0.93).
ISPC — iSpecimen Inc.: What the Facts Mean to a Prospective Investor
1. Roarable Rating Brief: What This Means to a Prospective Investor
iSpecimen Inc. (ISPC) earns a live Roarable RQD composite score of 30/100, corresponding to a E letter grade (Roarable Strong Sell) at a spot price of $0.83 (+0.82% 1D, market capitalization $2.1M).
- Fundamental Cash Engine (9/20): Anchored by return on invested capital (ROIC) of -35.0%, gross margin of 11.2%, operating margin of -60.0%, and free cash flow yield of —.
- Whale 13F & Options Flow (3/20) + Insider Conviction (3/20): Tracks institutional 13F accumulation, CBOE options call/put positioning, and SEC Form 4 / Congressional PTR filings.
- Macro Regime Fit (7/20) + Forensic Balance Sheet (8/20): Incorporates a 1.00x equity beta, Altman Z-Score of N/A, Piotroski F-Score of 3/9, and Debt/Equity of N/A.
2. Business Model, Unit Margins & SEC Financial Trajectory
ISpecimen Inc. (ISPC) is a NASDAQ-listed issuer classified in the Health Care sector and the Biotechnology: Commercial Physical & Biological Resarch industry. Gross margin is reported at 11.2% per the market data section.
In its latest audited SEC EDGAR 10-K filing for FY2025 (filed 2025-12-31), iSpecimen Inc. (ISPC) reported $1.9M in annual revenue (up from $9.3M in FY2024, -79.2% YoY) and -$10.5M in GAAP net income. Over the multi-year SEC filing window from FY2023 ($9.9M revenue, -$11.1M net income) through FY2025, ISPC scaled operating cash flow to -$4.2M and free cash flow to -$4.2M, backed by $9.5M in total assets against $0 in total debt.
3. Institutional Bull vs. Bear Thesis & Valuation Tradeoff
- 🐂 Primary Bull Case (E • RQD 30/100): Established market leader in Health Care with deep daily trading liquidity. Free cash flow yield of — and institutional whale pillar of 3/20. With Fundamental Cash Engine at 9/20 and Institutional Whale Flow at 3/20, sustained execution supports upside toward the upper end of the $0.75 – $32.96 52-week range.
- 🐻 Primary Bear Case & Valuation Risk: Company executives have done more routine share selling than personal cash buying lately. Investors must weigh current valuation against -60.0% operating margins and a 1.00x macro beta.
4. 2nd-Order Butterfly Ripples & Key Questions to Watch
Operating in Biotechnology: Commercial Physical & Biological Resarch (Health Care), ISPC carries a macro regime beta of 1.00 and gross margin of 11.2%.
- Key Question #1: Can ISPC sustain or expand its -60.0% operating margin and -35.0% ROIC against Biotechnology: Commercial Physical & Biological Resarch peers over the next 4 quarters?
- Key Question #2: Following FY2025 revenue of $1.9M and free cash flow of -$4.2M, how will capital allocation balance growth reinvestment against $0 in total debt?
- Key Question #3: How sensitive is ISPC's equity valuation to Health Care capital spending cycles and macro interest-rate shifts (Beta 1.00x)?
ISPC Live News Feed, Press Releases & Catalyst Wire
Real-time company headlines, analyst actions, and sector developments for iSpecimen Inc. (ISPC) • Click "Debate This Headline" to argue it in the Roar Pit below
Stock Titan report covering iSpecimen Inc. (ISPC) market action, institutional positioning, and fundamental catalysts.
Benzinga report covering iSpecimen Inc. (ISPC) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering iSpecimen Inc. (ISPC) market action, institutional positioning, and fundamental catalysts.
https://www.siam.in/ report covering iSpecimen Inc. (ISPC) market action, institutional positioning, and fundamental catalysts.
Gainers NRX Pharmaceuticals (NASDAQ:NRXP) shares increased by 12.0% to $2.98 during Friday's pre-market session. The market value of their outstanding shares is at $115.1 million. Intensity Therapeutics
Postmarket movers for Oct. 29, 2026: top after-hours gainers included SLGB, BURU and WKHS, while GCTK, LNAI and ATEC led the decliners.
Woburn, Massachusetts--(Newsfile Corp. - October 29, 2026) - iSpecimen Inc. (NASDAQ: ISPC) ("iSpecimen" or the "Company"), a provider of human biospecimens, today announced expanded access to fully consented, prospective
Gainers Biohaven (NYSE:BHVN) shares increased by 39.3% to $16.37 during Thursday's pre-market session. The company's market cap stands at $1.7 billion. Vogenx (NASDAQ:VOGX) stock rose 22.05% to $24.89. The
ISPC Bull vs. Bear Conversation Board — What's Your Call at $0.83?
Cash of $6.9M in FY 2025 exceeds that year's -$4.2M free cash flow outflow, per the SEC financials.
Long ISPC at $0.83 targeting $1.10. Cash of $6.9M in FY 2025 exceeds that year's -$4.2M free cash flow outflow, per the SEC financials.. Institutional whale score is 3/20 and the risk/reward vs. the $0.75 52-week low is skewed heavily in favor of bulls.
@ForensicBear Fair point on current EV/EBITDA multiples, but you're ignoring the forward operating leverage in Biotechnology: Commercial Physical & Biological Resarch. If gross margin (11.2%) holds, EPS grows into the multiple faster than bears think.
Net income was negative in every reported period while revenue fell from $9.9M to $1.9M, per the SEC financials.
Fading this rally in ISPC at $0.83. Net income was negative in every reported period while revenue fell from $9.9M to $1.9M, per the SEC financials.. With a beta of 1.0 and the stock sitting at $0.83 (52-wk range $0.75–$32.96), the easy multiple expansion is already priced in.