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UNCY (31) IMUX (33) EQ (31) TLSA (47) ⌘ Pro Terminal β†’

OnKure Therapeutics Inc. (Class A) (OKUR) Options Positioning, Max Pain & Unusual Sweeps

$2.59 -1.14% NASDAQ β€’ Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $2.58

OnKure Therapeutics Inc. (Class A) (OKUR) carries a Roarable Rating of E (Strong Sell) with 34/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.

ROARABLE E β€’ RED ALERT Cap $104.9M
πŸ“€ Share Live RQD Speedometer Card: 𝕏 Post Reddit StockTwits ⬇ Live SVG Card
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πŸ€– Mara Quenwick β€’ AI Quant Lead (Click for Instant Brief) Is OKUR stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
β–Ό

As of 2026-11-03, OnKure Therapeutics Inc. (Class A) (NASDAQ: OKUR) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 34/100 at a spot price of $2.59 (-1.14% 1D, market cap $104.9M). Pillar breakdown: Fundamental Cash Engine 7/20, Institutional 13F & Options Flow 5/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 7/20, and Executive Insider Alignment 5/20. Across 1015 tracked Health Care issuers, OKUR ranks #634 in composite RQD confidence.

βœ“ Pre-computed one-to-many AI Quant brief
πŸ€– Ellis Vennor β€’ AI Peer & Flow Quant (Click for Instant Brief) How does OKUR compare to UNCY and IMUX in the Health Care sector?
β–Ό

Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), OKUR carries a Roarable E (34/100 RQD), trailing P/E of N/A, gross margin of β€”, and ROIC of -35.0%. By comparison, UNCY (Unicycive Therapeutics Inc.) holds a E grade (31/100 RQD, P/E N/A, ROIC -35.0%, cap $104.2M) and IMUX (Immunic Inc.) posts a E grade (33/100 RQD, P/E N/A, ROIC -35.0%, cap $102.5M). Among the 5-stock peer group, OKUR leads on earnings multiple (N/A) while OKUR leads on capital efficiency (-35.0% ROIC).

βœ“ Pre-computed one-to-many AI Quant brief
πŸ€– Gideon Ashmere β€’ AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for OKUR?
β–Ό

Per OKUR's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001637715), OnKure Therapeutics Inc. (Class A) generated $176.3M in revenue (+15.7% YoY), -$59.5M in net income, and -$51.9M in free cash flow against $62.1M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.

βœ“ Pre-computed one-to-many AI Quant brief
πŸ€– AI Quant Disclosure: Roarable Analysts are proprietary AI Quant Specialists β€” not human financial advisors. Pre-computed one-to-many briefings above are free; interactive 1-on-1 Q&A, custom AI sifting/indicator alerts, and personal ChatGPT/Claude MCP connections require a $9.95/mo Pro account (currently waitlist-only).
INTERACTIVE SCENARIO DECK:
πŸ›‘οΈ Portfolio Crash X-Ray
EXT / AFTER-HRS: $2.58 (-0.40%)🧬 Disciplined Float (+0.72% YoY Shares)βš™οΈ Cash Engine: 7/20 (D-) β€’ 0% FCF Margin
Verify 90D Bucket Audit β†’
πŸ“Š Historical Track Record Warning: Scores below 50 (34/100 Β· E) historically underperformed SPY in 71% of rolling 90-day windows (-8.7% avg 90D alpha vs SPY β€’ 29.0% hit rate).
Audit Bucket Track Record β†’
RQD QUANT TACHOMETERRED ALERT β€’ E
025507510034
3-of-3 Quant Analysts Bearish Warning
Cash
SEC
Whale

Impersonal quantitative research (0–100 RQD rubric) β€” not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR RQD RADARRw E Β· Rk D-
Cash (7)Whales (5)SEC (10)Macro (7)CEO (5)
Each axis scored 0–20
12M PRICE TARGET CONE-10.8% Base Target
$6 Bull$2 Base$2 Bear
πŸ“¬ FREE OKUR RATING-CHANGE & BRIEFING ALERTSManage / Unsubscribe
WHALE OPTIONS SNAPSHOT: β€” (No Active Options Snapshot on file for OKUR)Realized 20D OHLCV Swing Band: Β±12.5%
Deterministic 5-Pillar Attribution (34/100 Composite)
πŸ” WHY OKUR SCORES 34/100 (E) β€” TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag
β–² #1 Bullish Driver: SEC 10-K Forensic Risk+10/20 pts (29% of score)

Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) β€’ Piotroski F-Score 2/9

β–² #2 Bullish Driver: Cash Engine Quality+7/20 pts (21% of score)

SEC XBRL FY 2025 (10-K): 0% FCF Margin ($0 FCF) & 52% Gross Margin

β–Ό #1 Drag / Risk Factor: Insider Conviction & Share Dilution5/20 pts (-15 pt drag)

Disciplined Float (+0.72% YoY Shares) & executive Form 4 sales trim 15 pts from alignment

πŸ“ˆ PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 β†’ Q2 β†’ Q3 β†’ Current
Q1 (-3Q)
26
Grade E$2.25+2.2% Next Q
Q2 (-2Q)
29
Grade E$2.30+14.3% Next Q
Q3 (-1Q)
31
Grade E$2.63-1.5% Next Q
Current
34
Grade E$2.59-8.7% Hist 90D Ξ±
Trajectory: E (26) β†’ E (34)Full Audit β†’
βš”οΈ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER

βš”οΈ Adversarial Opposing Case: What Could Spark a OKUR Turnaround Squeeze

Gideon Ashmere Forensic Desk β†’

While OKUR currently carries a cautious 34/100 (E) rating due to Insider Conviction & Share Dilution (5/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.

πŸš€ Contrarian Squeeze Trigger #1

Established market leader in Health Care with deep daily trading liquidity.

πŸš€ Contrarian Squeeze Trigger #2

Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($2.83) and Max Pain ($2.72) forces dealer call-delta covering toward $5.65.

πŸš€ Contrarian Squeeze Trigger #3

Forensic Repair Trigger: Halting share dilution (Disciplined Float (+0.72% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.

🎲 LIVE PREDICTION MARKET ODDS TIED TO $OKURβ€’ $2.4M Crowd Pool β€’ Kalshi / Polymarket Composite
Contract: β€œOKUR Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMA”
YES 34%NO 66%Trade / Inspect Odds β†’
CALL VS. PUT WHALE SHARE
β€” (No Active Options Snapshot)
Put/Call Ratio: β€” (No Active Options Snapshot)
MAX-PAIN EXPIRATION MAGNET
β€” (No Active Options Snapshot)
No active options chain max-pain snapshot on file
HISTORICAL 20D VOLATILITY SWING
Β±12.5%
Derived from 20D OHLCV bars (No Active Options Snapshot)

Active Strike Call vs. Put Concentration Ladder (OKUR)

β€” (No Active Options Snapshot) β€” No unusual CBOE strike concentration anomalies recorded in the current database snapshot for OKUR.

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Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring OKUR)

  • βœ“Walkthrough of OKUR's RQD Radar, SEC cash-conversion gap & downside invalidation levels
  • βœ“3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
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OKUR // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: -42.70%β–Ό DESCENDING CHANNEL
2026-11-04O $2.62H $2.62L $2.59C $2.59VOL 500.8K
RES: $3.83SUP: $1.69SMA50: $2.83SMA200: $3.61
$4.98$4.18$3.37$2.57$1.76RES $3.83SUP $1.69$2.592026-05-052026-06-182026-08-052026-09-212026-11-04
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

OKUR Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

πŸ¦‹ OKUR Butterfly Map β†’ + Track OKUR β†’
Share Count & Dilution Monitor

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle
8.0%/yr Implied 5Y Growth

vs. +15.7% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger

No active Ellis Vennor swing setup published on OKUR today. View full Setup Ledger β†’

πŸ¦‹ Documented & Second-Order Butterfly Connections Open Graph β†’

No direct multi-tier Butterfly edges indexed yet for OKUR. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video
🎬 No recent verified company-specific video clip queued for OKUR today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk β†’
DETERMINISTIC MULTI-FACTOR EQUITY AUDIT β€’ SEC EDGAR XBRL Γ— RQD PEER BENCHMARK

πŸ“Š Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (OKUR)

Health Care Rank #634 of 1015 βš”οΈ UNCY vs OKUR Full Matrix β†’

1. Head-to-Head Health Care Peer Comparison (OKUR vs. UNCY, IMUX, EQ, TLSA)

Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)

Across 1015 tracked Health Care securities in the Roarable RQD universe, OnKure Therapeutics Inc. (Class A) (OKUR) ranks #634 by composite RQD confidence (34/100, grade E) and #644 by equity capitalization ($104.9M). Within this direct 5-issuer industry benchmark cohort, OKUR leads on earnings valuation at N/A trailing P/E, while OKUR leads on capital efficiency and profitability with -35.0% ROIC and β€” gross margin. TLSA currently holds the highest overall quantitative score in the immediate peer group at 47/100 (D) compared with OKUR at 34/100 (E).

Ticker / Company Roarable Grade RQD Score Trailing P/E Gross Margin ROIC 1D Change Market Cap Head-to-Head
OKUR ACTIVE
OnKure Therapeutics Inc. (Class A)
E 34/100 β€” β€” -35.0% -1.14% $104.9M Benchmark Subject
UNCY
Unicycive Therapeutics Inc.
E 31/100 β€” β€” -35.0% -6.68% $104.2M /uncy-vs-okur β†’
IMUX
Immunic Inc.
E 33/100 β€” β€” -35.0% -2.26% $102.5M /imux-vs-okur β†’
EQ
Equillium Inc.
E 31/100 β€” β€” -35.0% +0.73% $107.4M /eq-vs-okur β†’
TLSA
Tiziana Life Sciences Ltd.
D 47/100 β€” β€” β€” -16.25% $101.8M /tlsa-vs-okur β†’

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)

SEC EDGAR 10-K β€’ FILED 2025-12-31 β€’ CIK 0001637715 β†—

In its most recent audited fiscal period (FY2025, filed 2025-12-31), OnKure Therapeutics Inc. (Class A) (OKUR) reported GAAP revenue of $176.3M (+15.7% vs. FY2024 revenue of $152.3M , and +70.4% cumulative change since FY2023) , GAAP net income of -$59.5M, operating cash flow of -$51.8M, and free cash flow of -$51.9M (-1.4% YoY). On the balance sheet, OKUR closed FY2025 with $62.1M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 2/9).

Fiscal Period Filing Date Revenue Net Income Operating Cash Flow Free Cash Flow Total Assets Total Debt
FY2025 (FY) 2025-12-31 $176.3M -$59.5M -$51.8M -$51.9M $62.1M β€”
FY2024 (FY) 2024-12-31 $152.3M -$52.7M -$51.1M -$51.2M $114.9M β€”
FY2023 (FY) 2023-12-31 $103.4M -$35.3M -$34.5M -$34.5M β€” β€”

3. OKUR Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

βœ“ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is OKUR stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

As of 2026-11-03, OnKure Therapeutics Inc. (Class A) (NASDAQ: OKUR) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 34/100 at a spot price of $2.59 (-1.14% 1D, market cap $104.9M). Pillar breakdown: Fundamental Cash Engine 7/20, Institutional 13F & Options Flow 5/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 7/20, and Executive Insider Alignment 5/20. Across 1015 tracked Health Care issuers, OKUR ranks #634 in composite RQD confidence.

How does OKUR compare to UNCY and IMUX in the Health Care sector?

Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), OKUR carries a Roarable E (34/100 RQD), trailing P/E of N/A, gross margin of β€”, and ROIC of -35.0%. By comparison, UNCY (Unicycive Therapeutics Inc.) holds a E grade (31/100 RQD, P/E N/A, ROIC -35.0%, cap $104.2M) and IMUX (Immunic Inc.) posts a E grade (33/100 RQD, P/E N/A, ROIC -35.0%, cap $102.5M). Among the 5-stock peer group, OKUR leads on earnings multiple (N/A) while OKUR leads on capital efficiency (-35.0% ROIC).

What are the biggest fundamental strengths and SEC risk factors for OKUR?

Per OKUR's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001637715), OnKure Therapeutics Inc. (Class A) generated $176.3M in revenue (+15.7% YoY), -$59.5M in net income, and -$51.9M in free cash flow against $62.1M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.

Where is OKUR trading relative to its 50-day, 200-day, and 52-week technical levels?

OKUR last traded at $2.59 (-1.14% on volume of 500,843 shares), positioning the stock -8.48% below its 50-day simple moving average ($2.83) and -28.25% below its 200-day simple moving average ($3.61). Across its 52-week range of $2.01 to $5.38, OKUR sits at the 17.2% percentile with a 14-day RSI of 49.3 (NEUTRAL RANGE) and an implied next-earnings move of Β±12.5% ($2.27 to $2.91).

Direct Sub-Reports: OKUR RQD Cockpit OKUR 12M Forecast OKUR Earnings & Move OKUR Dividends & DRIP OKUR Insiders & 13F OKUR Whale Options OKUR Profit Sankey OKUR News & Why
ROARABLE RATING BRIEF β€’ RQD 34/100 (E) βœ“ SEC XBRL & RQD VERIFIED

OKUR β€” OnKure Therapeutics Inc. (Class A): What the Facts Mean to a Prospective Investor

Methodology: RQD v6.2 Deterministic 5-Pillar & SEC XBRL Audit
Updated: 2025-12-31

1. Roarable Rating Brief: What This Means to a Prospective Investor

OnKure Therapeutics Inc. (Class A) (OKUR) earns a live Roarable RQD composite score of 34/100, corresponding to a E letter grade (Roarable Strong Sell) at a spot price of $2.59 (-1.14% 1D, market capitalization $104.9M).

  • Fundamental Cash Engine (7/20): Anchored by return on invested capital (ROIC) of -35.0%, gross margin of β€”, operating margin of β€”, and free cash flow yield of β€”.
  • Whale 13F & Options Flow (5/20) + Insider Conviction (5/20): Tracks institutional 13F accumulation, CBOE options call/put positioning, and SEC Form 4 / Congressional PTR filings.
  • Macro Regime Fit (7/20) + Forensic Balance Sheet (10/20): Incorporates a 1.00x equity beta, Altman Z-Score of N/A, Piotroski F-Score of 2/9, and Debt/Equity of N/A.

2. Business Model, Unit Margins & SEC Financial Trajectory

OnKure Therapeutics Inc. (Class A) is listed on NASDAQ under the ticker OKUR. It operates in the Health Care sector, within the Biotechnology: Pharmaceutical Preparations industry. Reported revenue is β€” in each of the listed fiscal years, so the company's current income is derived from no sales.

In its latest audited SEC EDGAR 10-K filing for FY2025 (filed 2025-12-31), OnKure Therapeutics Inc. (Class A) (OKUR) reported $176.3M in annual revenue (up from $152.3M in FY2024, +15.7% YoY) and -$59.5M in GAAP net income. Over the multi-year SEC filing window from FY2023 ($103.4M revenue, -$35.3M net income) through FY2025, OKUR scaled operating cash flow to -$51.8M and free cash flow to -$51.9M, backed by $62.1M in total assets against $0 in total debt.

3. Institutional Bull vs. Bear Thesis & Valuation Tradeoff

  • πŸ‚ Primary Bull Case (E β€’ RQD 34/100): Established market leader in Health Care with deep daily trading liquidity. Free cash flow yield of β€” and institutional whale pillar of 5/20. With Fundamental Cash Engine at 7/20 and Institutional Whale Flow at 5/20, sustained execution supports upside toward the upper end of the $2.01 – $5.38 52-week range.
  • 🐻 Primary Bear Case & Valuation Risk: Company executives have done more routine share selling than personal cash buying lately. Investors must weigh current valuation against β€” operating margins and a 1.00x macro beta.

4. 2nd-Order Butterfly Ripples & Key Questions to Watch

Operating in Biotechnology: Pharmaceutical Preparations (Health Care), OKUR carries a macro regime beta of 1.00 and gross margin of β€”.

  • Key Question #1: Can OKUR sustain or expand its β€” operating margin and -35.0% ROIC against Biotechnology: Pharmaceutical Preparations peers over the next 4 quarters?
  • Key Question #2: Following FY2025 revenue of $176.3M and free cash flow of -$51.9M, how will capital allocation balance growth reinvestment against $0 in total debt?
  • Key Question #3: How sensitive is OKUR's equity valuation to Health Care capital spending cycles and macro interest-rate shifts (Beta 1.00x)?

OKUR Live News Feed, Press Releases & Catalyst Wire

Real-time company headlines, analyst actions, and sector developments for OnKure Therapeutics Inc. (Class A) (OKUR) β€’ Click "Debate This Headline" to argue it in the Roar Pit below

πŸ’¬ Jump to OKUR Debate Forum (3) ↓
πŸ”₯ THE ROAR PIT β€’ LIVE COMMUNITY DEBATE 3 Active Posts & Replies

OKUR Bull vs. Bear Conversation Board β€” What's Your Call at $2.59?

πŸ‚ 67% BULLISH CONVICTION COMMUNITY TUG-OF-WAR ON OKUR 🐻 33% BEARISH CONVICTION
1. Pick Your Side on OKUR:
πŸ’‘ Tip: Back up your call with a price target or RQD metric to get upvoted to the top.
TA TapeReader_Pro RQD DEBATE OPENER β€’ Price Action & Volume Trader πŸ‚ BULLISH 🎯 Target: $3.14 (+19.8%)
πŸ“Œ Pinned Debate

Cash of $59.0M at FY 2025 provides a funded balance sheet alongside a 2.5 Altman Z-Score, though the source does not tie this to a pipe

Long OKUR at $2.62 targeting $3.14. Cash of $59.0M at FY 2025 provides a funded balance sheet alongside a 2.5 Altman Z-Score, though the source does not tie this to a pipeline.. Institutional whale score is 5/20 and the risk/reward vs. the $2.01 52-week low is skewed heavily in favor of bulls.

EarningsSniper πŸ‚ BULL

@ShortSeller_Dan Shorting a 5/20 institutional whale-flow stock at $2.62 is dangerous when funds are rotating into Health Care.

SH ShortSeller_Dan RQD DEBATE OPENER β€’ Forensic Short Bias 🐻 BEARISH 🎯 Target: $1.99 (-24.0%)
Spot @ $2.62

Zero revenue, a -35% ROIC, a 0% FCF yield, and a 2/9 Piotroski F-Score point to a loss-making business with weak cash generation.

Sitting on the sidelines or leaning short OKUR above $2.62. Zero revenue, a -35% ROIC, a 0% FCF yield, and a 2/9 Piotroski F-Score point to a loss-making business with weak cash generation.. Until Fundamental Cash Engine (7/20) and FCF yield (0.0%) inflect higher, upside is capped near $5.38.

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