Gainers CareDx (NASDAQ:CDNA) shares rose 22.2% to $87.42 during Friday's regular session. The company's market cap stands at $3.7 billion. As per the press release, Q3 earnings came out yesterday. Jin Medical
Why PMN Stock dropped -9.37% Today — RQD Quant Desk Flash
ProMIS Neurosciences Inc. (ON) (PMN) carries a Roarable Rating of D- (Sell) with 35/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief)
Is PMN stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-03, ProMIS Neurosciences Inc. (ON) (NASDAQ: PMN) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 35/100 at a spot price of $3.00 (-9.37% 1D, market cap $29.7M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 3/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 9/20, and Executive Insider Alignment 5/20. Across 1015 tracked Health Care issuers, PMN ranks #604 in composite RQD confidence.
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief)
How does PMN compare to AARD and FLNA in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), PMN carries a Roarable D- (35/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, AARD (Aardvark Therapeutics Inc.) holds a E grade (33/100 RQD, P/E N/A, ROIC -35.0%, cap $29.8M) and FLNA (Filana Therapeutics Inc.) posts a D- grade (38/100 RQD, P/E N/A, ROIC -35.0%, cap $30.0M). Among the 5-stock peer group, PMN leads on earnings multiple (N/A) while RMTI leads on capital efficiency (-10.6% ROIC).
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief)
What are the biggest fundamental strengths and SEC risk factors for PMN?
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Per PMN's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001374339), ProMIS Neurosciences Inc. (ON) generated $112.5M in revenue (+138.7% YoY), -$39.7M in net income, and -$28.1M in free cash flow against $9.2M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 1/9
FRED Regime × Technicals: 2% of 52W Range • RSI-14 at 28.2 (OVERSOLD (<32))
Put hedging (50% put share) caps near-term gamma upside (-16 pts vs max)
⚔️ Adversarial Opposing Case: What Could Spark a PMN Turnaround Squeeze
While PMN currently carries a cautious 35/100 (D-) rating due to Whale & Options Positioning (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
Established market leader in Health Care with deep daily trading liquidity.
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($10.80) and Max Pain ($3.15) forces dealer call-delta covering toward $28.77.
Forensic Repair Trigger: Halting share dilution (Disciplined Float (+0.72% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
Why PMN Stock dropped -9.37% Today — RQD Quant Desk Flash
ProMIS Neurosciences Inc. (ON) (PMN) dropped -9.37% to $3.00, trading at 2% of its 52-week range ($2.84 – $27.4). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 2% of its 52-week range ($2.84 – $27.4) with RSI-14 at 28.2 (OVERSOLD (<32)).
- ▸Volatility Profile: Historical 20-day realized swing band of ±12.5% around $3.00 (no active unusual options sweep snapshot on file).
- ▸Fundamental Anchor: Roarable D- (Sell) backed by 52% gross margin and $0 annual free cash flow.
Gainers NRX Pharmaceuticals (NASDAQ:NRXP) shares increased by 12.0% to $2.98 during Friday's pre-market session. The market value of their outstanding shares is at $115.1 million. Intensity Therapeutics
The mean of analysts' price targets for Promis Neurosciences (PMN) points to a 293% upside in the stock. While this highly sought-after metric has not proven reasonably effective, strong agreement among analysts in raisi
HCA's Q3 results could benefit from higher admissions, occupancy and inpatient revenues, but rising costs and fewer outpatient surgeries cloud the outlook.
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Universal Health Services' Q3 revenues are expected to rise on higher patient admissions, but surging operating costs and wage pressures could weigh on earnings growth.
Roth Capital analyst Boobalan Pachaiyappan maintains ProMIS Neurosciences (NASDAQ:PMN) with a Buy and lowers the price target from $29 to $15.
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CI's Q3 revenues are poised to rise on pharmacy and premium growth, but declining Evernorth profits and higher medical costs could weigh on earnings.
Company to host investor conference call and webcast at 4:30 p.m. ET.Cambridge, Massachusetts, Nov. 03, 2026 (GLOBE NEWSWIRE) -- ProMIS Neurosciences Inc. (Nasdaq: PMN), a clinical-stage biotechnology company developing
Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring PMN)
- ✓Walkthrough of PMN's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
- ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
PMN Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. +138.7% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on PMN today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for PMN. Explore sector supply chains on /butterfly.
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (PMN)
1. Head-to-Head Health Care Peer Comparison (PMN vs. AARD, FLNA, NXTC, RMTI)
Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)Across 1015 tracked Health Care securities in the Roarable RQD universe, ProMIS Neurosciences Inc. (ON) (PMN) ranks #604 by composite RQD confidence (35/100, grade D-) and #799 by equity capitalization ($29.7M). Within this direct 5-issuer industry benchmark cohort, PMN leads on earnings valuation at N/A trailing P/E, while RMTI leads on capital efficiency and profitability with -10.6% ROIC and 16.9% gross margin. FLNA currently holds the highest overall quantitative score in the immediate peer group at 38/100 (D-) compared with PMN at 35/100 (D-).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| PMN
ACTIVE
ProMIS Neurosciences Inc. (ON) | D- | 35/100 | — | — | -35.0% | -9.37% | $29.7M | Benchmark Subject |
| AARD Aardvark Therapeutics Inc. | E | 33/100 | — | — | -35.0% | -11.76% | $29.8M | /aard-vs-pmn → |
| FLNA Filana Therapeutics Inc. | D- | 38/100 | — | — | -35.0% | -9.81% | $30.0M | /flna-vs-pmn → |
| NXTC NextCure Inc. | D- | 37/100 | — | — | -35.0% | -9.75% | $28.9M | /nxtc-vs-pmn → |
| RMTI Rockwell Medical Inc. | E | 23/100 | — | 16.9% | -10.6% | -2.26% | $28.5M | /rmti-vs-pmn → |
2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)
SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001374339 ↗In its most recent audited fiscal period (FY2025, filed 2025-12-31), ProMIS Neurosciences Inc. (ON) (PMN) reported GAAP revenue of $112.5M (+138.7% vs. FY2024 revenue of $47.1M , and +181.6% cumulative change since FY2023) , GAAP net income of -$39.7M, operating cash flow of -$28.1M, and free cash flow of -$28.1M (-3.4% YoY). On the balance sheet, PMN closed FY2025 with $9.2M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 1/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $112.5M | -$39.7M | -$28.1M | -$28.1M | $9.2M | — |
| FY2024 (FY) | 2024-12-31 | $47.1M | $2.8M | -$27.2M | -$27.2M | $18.9M | — |
| FY2023 (FY) | 2023-12-31 | $39.9M | -$13.2M | -$10.8M | -$10.8M | — | — |
3. PMN Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs PMN stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-03, ProMIS Neurosciences Inc. (ON) (NASDAQ: PMN) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 35/100 at a spot price of $3.00 (-9.37% 1D, market cap $29.7M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 3/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 9/20, and Executive Insider Alignment 5/20. Across 1015 tracked Health Care issuers, PMN ranks #604 in composite RQD confidence.
How does PMN compare to AARD and FLNA in the Health Care sector?
Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), PMN carries a Roarable D- (35/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, AARD (Aardvark Therapeutics Inc.) holds a E grade (33/100 RQD, P/E N/A, ROIC -35.0%, cap $29.8M) and FLNA (Filana Therapeutics Inc.) posts a D- grade (38/100 RQD, P/E N/A, ROIC -35.0%, cap $30.0M). Among the 5-stock peer group, PMN leads on earnings multiple (N/A) while RMTI leads on capital efficiency (-10.6% ROIC).
What are the biggest fundamental strengths and SEC risk factors for PMN?
Per PMN's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001374339), ProMIS Neurosciences Inc. (ON) generated $112.5M in revenue (+138.7% YoY), -$39.7M in net income, and -$28.1M in free cash flow against $9.2M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Where is PMN trading relative to its 50-day, 200-day, and 52-week technical levels?
PMN last traded at $3.00 (-9.37% on volume of 3,536,154 shares), positioning the stock -72.22% below its 50-day simple moving average ($10.80) and -76.64% below its 200-day simple moving average ($12.84). Across its 52-week range of $2.84 to $27.40, PMN sits at the 0.7% percentile with a 14-day RSI of 28.2 (OVERSOLD (<32)) and an implied next-earnings move of ±12.5% ($2.62 to $3.38).
PMN — ProMIS Neurosciences Inc. (ON): What the Facts Mean to a Prospective Investor
1. Roarable Rating Brief: What This Means to a Prospective Investor
ProMIS Neurosciences Inc. (ON) (PMN) earns a live Roarable RQD composite score of 35/100, corresponding to a D- letter grade (Roarable Sell) at a spot price of $3.00 (-9.37% 1D, market capitalization $29.7M).
- Fundamental Cash Engine (8/20): Anchored by return on invested capital (ROIC) of -35.0%, gross margin of —, operating margin of —, and free cash flow yield of —.
- Whale 13F & Options Flow (3/20) + Insider Conviction (5/20): Tracks institutional 13F accumulation, CBOE options call/put positioning, and SEC Form 4 / Congressional PTR filings.
- Macro Regime Fit (9/20) + Forensic Balance Sheet (10/20): Incorporates a 1.00x equity beta, Altman Z-Score of N/A, Piotroski F-Score of 1/9, and Debt/Equity of N/A.
2. Business Model, Unit Margins & SEC Financial Trajectory
ProMIS Neurosciences Inc. (ON) is a NASDAQ-listed issuer in the Health Care sector, within the Biotechnology: Pharmaceutical Preparations industry..1B. Reported revenue is — across the periods provided.
In its latest audited SEC EDGAR 10-K filing for FY2025 (filed 2025-12-31), ProMIS Neurosciences Inc. (ON) (PMN) reported $112.5M in annual revenue (up from $47.1M in FY2024, +138.7% YoY) and -$39.7M in GAAP net income. Over the multi-year SEC filing window from FY2023 ($39.9M revenue, -$13.2M net income) through FY2025, PMN scaled operating cash flow to -$28.1M and free cash flow to -$28.1M, backed by $9.2M in total assets against $0 in total debt.
3. Institutional Bull vs. Bear Thesis & Valuation Tradeoff
- 🐂 Primary Bull Case (D- • RQD 35/100): Established market leader in Health Care with deep daily trading liquidity. Free cash flow yield of — and institutional whale pillar of 3/20. With Fundamental Cash Engine at 8/20 and Institutional Whale Flow at 3/20, sustained execution supports upside toward the upper end of the $2.84 – $27.40 52-week range.
- 🐻 Primary Bear Case & Valuation Risk: Company executives have done more routine share selling than personal cash buying lately. Investors must weigh current valuation against — operating margins and a 1.00x macro beta.
4. 2nd-Order Butterfly Ripples & Key Questions to Watch
Operating in Biotechnology: Pharmaceutical Preparations (Health Care), PMN carries a macro regime beta of 1.00 and gross margin of —.
- Key Question #1: Can PMN sustain or expand its — operating margin and -35.0% ROIC against Biotechnology: Pharmaceutical Preparations peers over the next 4 quarters?
- Key Question #2: Following FY2025 revenue of $112.5M and free cash flow of -$28.1M, how will capital allocation balance growth reinvestment against $0 in total debt?
- Key Question #3: How sensitive is PMN's equity valuation to Health Care capital spending cycles and macro interest-rate shifts (Beta 1.00x)?
PMN Live News Feed, Press Releases & Catalyst Wire
Real-time company headlines, analyst actions, and sector developments for ProMIS Neurosciences Inc. (ON) (PMN) • Click "Debate This Headline" to argue it in the Roar Pit below
Gainers CareDx (NASDAQ:CDNA) shares rose 22.2% to $87.42 during Friday's regular session. The company's market cap stands at $3.7 billion. As per the press release, Q3 earnings came out yesterday. Jin Medical
Gainers NRX Pharmaceuticals (NASDAQ:NRXP) shares increased by 12.0% to $2.98 during Friday's pre-market session. The market value of their outstanding shares is at $115.1 million. Intensity Therapeutics
The mean of analysts' price targets for Promis Neurosciences (PMN) points to a 293% upside in the stock. While this highly sought-after metric has not proven reasonably effective, strong agreement among analysts in raisi
HCA's Q3 results could benefit from higher admissions, occupancy and inpatient revenues, but rising costs and fewer outpatient surgeries cloud the outlook.
Gainers Pomdoctor (NASDAQ:POM) stock moved upwards by 115.1% to $1.43 during Wednesday's regular session. The market value of their outstanding shares is at $4.9 million. Stablecoin Development (AMEX:SDEV) stock
Universal Health Services' Q3 revenues are expected to rise on higher patient admissions, but surging operating costs and wage pressures could weigh on earnings growth.
Roth Capital analyst Boobalan Pachaiyappan maintains ProMIS Neurosciences (NASDAQ:PMN) with a Buy and lowers the price target from $29 to $15.
Nasdaq unusual-volume stocks on Nov. 3, 2026 included PARA up 101%, CENN down 86.15%, and other names trading above their 50-day average volume.
PMN Bull vs. Bear Conversation Board — What's Your Call at $3.00?
Beta of 1.0 and a 52-week range of $10.24 - $12.68 show a tightly held price, with the stock trading near the top of that band at 11.08
Don't sleep on PMN's setup in Health Care. Beta of 1.0 and a 52-week range of $10.24 - $12.68 show a tightly held price, with the stock trading near the top of that band at 11.08.. Beta of 1.0 means it moves fast when momentum turns, and the 5-pillar RQD gauge (35/100) backs up the fundamental quality.
Both sides have a point here — PMN's 10/20 balance sheet score keeps downside contained, so the real swing factor next earnings call is backlog and FCF conversion.
Operating income fell from -$14.3M in FY 2023 to -$40.2M in FY 2025 while cash dropped to $6.1M, leaving ROIC at -35% and FCF at -$28.1
Sitting on the sidelines or leaning short PMN above $3.31. Operating income fell from -$14.3M in FY 2023 to -$40.2M in FY 2025 while cash dropped to $6.1M, leaving ROIC at -35% and FCF at -$28.1M.. Until Fundamental Cash Engine (8/20) and FCF yield (0.0%) inflect higher, upside is capped near $27.40.