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Stock Ratings / Health Care / PRQR / news
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Why PRQR Stock dropped -5.04% Today — RQD Quant Desk Flash

$1.32 -5.04% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $1.31

ProQR Therapeutics N.V. (PRQR) carries a Roarable Rating of D (Sell) with 44/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.

ROARABLE D • SELL / AVOID Cap $186.3M
📤 Share Live RQD Speedometer Card: 𝕏 Post Reddit StockTwits ⬇ Live SVG Card
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🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief) Is PRQR stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
▼

As of 2026-11-03, ProQR Therapeutics N.V. (NASDAQ: PRQR) is rated D (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 44/100 at a spot price of $1.32 (-5.04% 1D, market cap $186.3M). Pillar breakdown: Fundamental Cash Engine 12/20, Institutional 13F & Options Flow 3/20, SEC Balance-Sheet Forensics 13/20, FRED Macro Regime Fit 7/20, and Executive Insider Alignment 9/20. Across 1015 tracked Health Care issuers, PRQR ranks #394 in composite RQD confidence.

✓ Pre-computed one-to-many AI Quant brief
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief) How does PRQR compare to BBOT and UPB in the Health Care sector?
▼

Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), PRQR carries a Roarable D (44/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of —. By comparison, BBOT (BridgeBio Oncology Therapeutics Inc.) holds a E grade (33/100 RQD, P/E N/A, ROIC -35.0%, cap $185.2M) and UPB (Upstream Bio Inc.) posts a E grade (29/100 RQD, P/E N/A, ROIC -35.0%, cap $183.5M). Among the 5-stock peer group, PRQR leads on earnings multiple (N/A) while BBOT leads on capital efficiency (-35.0% ROIC).

✓ Pre-computed one-to-many AI Quant brief
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for PRQR?
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For ProQR Therapeutics N.V. (PRQR), key quantitative strengths include Established market leader in Health Care with deep daily trading liquidity and sector rank #394 in Health Care, while primary risk factors center on Company executives have done more routine share selling than personal cash buying lately and Sensitive to high interest rates and tighter Federal Reserve market liquidity.. Institutional options positioning shows a 50% call / 50% put premium split.

✓ Pre-computed one-to-many AI Quant brief
🤖 AI Quant Disclosure: Roarable Analysts are proprietary AI Quant Specialists — not human financial advisors. Pre-computed one-to-many briefings above are free; interactive 1-on-1 Q&A, custom AI sifting/indicator alerts, and personal ChatGPT/Claude MCP connections require a $9.95/mo Pro account (currently waitlist-only).
INTERACTIVE SCENARIO DECK:
🛡️ Portfolio Crash X-Ray
EXT / AFTER-HRS: $1.31 (-1.10%)🧬 Disciplined Float (-0.40% YoY Shares)⚙️ Cash Engine: 12/20 (C-) • 0.1% FCF Margin
Verify 90D Bucket Audit →
📊 Historical Track Record Warning: Scores below 50 (44/100 · D) historically underperformed SPY in 71% of rolling 90-day windows (-6.5% avg 90D alpha vs SPY • 29.0% hit rate).
Audit Bucket Track Record →
RQD QUANT TACHOMETERSELL / AVOID • D
025507510044
Quant Analyst Panel Split (Battleground)
Cash
SEC
Whale

Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR RQD RADARRw D- · Rk D
Cash (12)Whales (3)SEC (13)Macro (7)CEO (9)
Each axis scored 0–20
12M PRICE TARGET CONE-6.1% Base Target
$3 Bull$1 Base$1 Bear
📬 FREE PRQR RATING-CHANGE & BRIEFING ALERTSManage / Unsubscribe
WHALE OPTIONS SNAPSHOT: — (No Active Options Snapshot on file for PRQR)Realized 20D OHLCV Swing Band: ±12.5%
Deterministic 5-Pillar Attribution (44/100 Composite)
🔍 WHY PRQR SCORES 44/100 (D) — TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag
▲ #1 Bullish Driver: SEC 10-K Forensic Risk+13/20 pts (30% of score)

Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 7/9

▲ #2 Bullish Driver: Cash Engine Quality+12/20 pts (27% of score)

SEC XBRL Trailing 12 Months: 0.1% FCF Margin ($5.2M FCF) & 52% Gross Margin

▼ #1 Drag / Risk Factor: Whale & Options Positioning4/20 pts (-16 pt drag)

Put hedging (50% put share) caps near-term gamma upside (-16 pts vs max)

📈 PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 → Q2 → Q3 → Current
Q1 (-3Q)
52
Grade C-$1.47-6.8% Next Q
Q2 (-2Q)
49
Grade D$1.37+2.9% Next Q
Q3 (-1Q)
47
Grade D$1.41-6.4% Next Q
Current
44
Grade D$1.32-6.5% Hist 90D α
Trajectory: C- (52) → D (44)Full Audit →
⚔️ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER

⚔️ Adversarial Opposing Case: What Could Spark a PRQR Turnaround Squeeze

Gideon Ashmere Forensic Desk →

While PRQR currently carries a cautious 44/100 (D) rating due to Whale & Options Positioning (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.

🚀 Contrarian Squeeze Trigger #1

Established market leader in Health Care with deep daily trading liquidity.

🚀 Contrarian Squeeze Trigger #2

Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($1.69) and Max Pain ($1.39) forces dealer call-delta covering toward $2.78.

🚀 Contrarian Squeeze Trigger #3

Forensic Repair Trigger: Halting share dilution (Disciplined Float (-0.40% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.

🎲 LIVE PREDICTION MARKET ODDS TIED TO $PRQR• $2.4M Crowd Pool • Kalshi / Polymarket Composite
Contract: “PRQR Beats Next Quarter EPS Consensus (Upcoming Quarter) & Holds Above 200D SMA”
YES 44%NO 56%Trade / Inspect Odds →
AUTOMATED RQD QUANT DESK MOVER BRIEFINGFull Market News Desk →

Why PRQR Stock dropped -5.04% Today — RQD Quant Desk Flash

ProQR Therapeutics N.V. (PRQR) dropped -5.04% to $1.32, trading at 8% of its 52-week range ($1.2 – $2.65). Stretched risk/reward at current multiples (steady margins) under elevated 10-year interest-rate pressure.

  • ▸Technical Tape: Trading at 8% of its 52-week range ($1.2 – $2.65) with RSI-14 at 36.6 (NEUTRAL RANGE).
  • ▸Volatility Profile: Historical 20-day realized swing band of ±12.5% around $1.32 (no active unusual options sweep snapshot on file).
  • ▸Fundamental Anchor: Roarable D (Sell) backed by 52% gross margin and $5.2M annual free cash flow.
Live PRQR Headlines & Catalysts
MARKET WIRETradingKey • 2d ago
Most Active Stocks Today: U.S. Market

TradingKey report covering ProQR Therapeutics N.V. (PRQR) market action, institutional positioning, and fundamental catalysts.

ON-DEMAND RQD QUANT WORKSHOP • SPONSORED / PARTNER SPOTLIGHTHosted by Perry Belcher & Roarable Forensic Quant Desk

Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring PRQR)

  • ✓Walkthrough of PRQR's RQD Radar, SEC cash-conversion gap & downside invalidation levels
  • ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
  • ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
RQD INSIDER CLUB WAITLIST$49/YR PLANNED
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PRQR // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: -19.02%📐 HORIZONTAL RANGE
2026-11-04O $1.39H $1.39L $1.32C $1.32VOL 644.2K
RES: $3.00SUP: $1.19SMA50: $1.69SMA200: $1.69
$2.55$2.18$1.82$1.45$1.09RES $3.00SUP $1.19$1.322026-05-052026-06-182026-08-052026-09-212026-11-04
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

PRQR Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

🦋 PRQR Butterfly Map → + Track PRQR →
Share Count & Dilution Monitor

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle
8.0%/yr Implied 5Y Growth

vs. +6.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger

No active Ellis Vennor swing setup published on PRQR today. View full Setup Ledger →

🦋 Documented & Second-Order Butterfly Connections Open Graph →

No direct multi-tier Butterfly edges indexed yet for PRQR. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video
🎬 No recent verified company-specific video clip queued for PRQR today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk →
DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK

📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (PRQR)

Health Care Rank #394 of 1015 ⚔️ BBOT vs PRQR Full Matrix →

1. Head-to-Head Health Care Peer Comparison (PRQR vs. BBOT, UPB, RNAC, WHWK)

Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)

Across 1015 tracked Health Care securities in the Roarable RQD universe, ProQR Therapeutics N.V. (PRQR) ranks #394 by composite RQD confidence (44/100, grade D) and #582 by equity capitalization ($186.3M). Within this direct 5-issuer industry benchmark cohort, PRQR leads on earnings valuation at N/A trailing P/E, while BBOT leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. PRQR currently leads its immediate peer cohort in composite quantitative strength at 44/100 (D).

Ticker / Company Roarable Grade RQD Score Trailing P/E Gross Margin ROIC 1D Change Market Cap Head-to-Head
PRQR ACTIVE
ProQR Therapeutics N.V.
D 44/100 — — — -5.04% $186.3M Benchmark Subject
BBOT
BridgeBio Oncology Therapeutics Inc.
E 33/100 — — -35.0% -11.83% $185.2M /bbot-vs-prqr →
UPB
Upstream Bio Inc.
E 29/100 — — -35.0% -1.76% $183.5M /upb-vs-prqr →
RNAC
Cartesian Therapeutics Inc.
E 15/100 — — -35.0% -2.31% $191.8M /rnac-vs-prqr →
WHWK
Whitehawk Therapeutics Inc.
E 24/100 — 89.4% -35.0% -3.70% $177.9M /whwk-vs-prqr →

2. PRQR Fundamental Profitability, Capital Efficiency & Balance-Sheet Forensics

TRAILING 12M & FORWARD QUANTITATIVE SNAPSHOT

ProQR Therapeutics N.V. (PRQR) operates in Biotechnology: Pharmaceutical Preparations (Health Care) with an equity capitalization of $186.3M, trailing P/E of N/A, forward P/E of N/A, and EV/EBITDA of N/A. Operating profitability registers a gross margin of —, operating margin of —, net profit margin of —, ROIC of —, and free cash flow yield of —, alongside an Altman Z-Score of N/A and Piotroski F-Score of N/A.

3. PRQR Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is PRQR stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

As of 2026-11-03, ProQR Therapeutics N.V. (NASDAQ: PRQR) is rated D (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 44/100 at a spot price of $1.32 (-5.04% 1D, market cap $186.3M). Pillar breakdown: Fundamental Cash Engine 12/20, Institutional 13F & Options Flow 3/20, SEC Balance-Sheet Forensics 13/20, FRED Macro Regime Fit 7/20, and Executive Insider Alignment 9/20. Across 1015 tracked Health Care issuers, PRQR ranks #394 in composite RQD confidence.

How does PRQR compare to BBOT and UPB in the Health Care sector?

Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), PRQR carries a Roarable D (44/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of —. By comparison, BBOT (BridgeBio Oncology Therapeutics Inc.) holds a E grade (33/100 RQD, P/E N/A, ROIC -35.0%, cap $185.2M) and UPB (Upstream Bio Inc.) posts a E grade (29/100 RQD, P/E N/A, ROIC -35.0%, cap $183.5M). Among the 5-stock peer group, PRQR leads on earnings multiple (N/A) while BBOT leads on capital efficiency (-35.0% ROIC).

What are the biggest fundamental strengths and SEC risk factors for PRQR?

For ProQR Therapeutics N.V. (PRQR), key quantitative strengths include Established market leader in Health Care with deep daily trading liquidity and sector rank #394 in Health Care, while primary risk factors center on Company executives have done more routine share selling than personal cash buying lately and Sensitive to high interest rates and tighter Federal Reserve market liquidity.. Institutional options positioning shows a 50% call / 50% put premium split.

Where is PRQR trading relative to its 50-day, 200-day, and 52-week technical levels?

PRQR last traded at $1.32 (-5.04% on volume of 644,203 shares), positioning the stock -21.89% below its 50-day simple moving average ($1.69) and -21.89% below its 200-day simple moving average ($1.69). Across its 52-week range of $1.20 to $2.65, PRQR sits at the 8.3% percentile with a 14-day RSI of 36.6 (NEUTRAL RANGE) and an implied next-earnings move of ±12.5% ($1.15 to $1.49).

Direct Sub-Reports: PRQR RQD Cockpit PRQR 12M Forecast PRQR Earnings & Move PRQR Dividends & DRIP PRQR Insiders & 13F PRQR Whale Options PRQR Profit Sankey PRQR News & Why
ROARABLE RATING BRIEF • RQD 44/100 (D) ✓ SEC XBRL & RQD VERIFIED

PRQR — ProQR Therapeutics N.V.: What the Facts Mean to a Prospective Investor

Methodology: RQD v6.2 Deterministic 5-Pillar & SEC XBRL Audit
Updated: 2026-11-03

1. Roarable Rating Brief: What This Means to a Prospective Investor

ProQR Therapeutics N.V. (PRQR) earns a live Roarable RQD composite score of 44/100, corresponding to a D letter grade (Roarable Sell) at a spot price of $1.32 (-5.04% 1D, market capitalization $186.3M).

  • Fundamental Cash Engine (12/20): Anchored by return on invested capital (ROIC) of —, gross margin of —, operating margin of —, and free cash flow yield of —.
  • Whale 13F & Options Flow (3/20) + Insider Conviction (9/20): Tracks institutional 13F accumulation, CBOE options call/put positioning, and SEC Form 4 / Congressional PTR filings.
  • Macro Regime Fit (7/20) + Forensic Balance Sheet (13/20): Incorporates a 1.00x equity beta, Altman Z-Score of N/A, Piotroski F-Score of N/A, and Debt/Equity of N/A.

2. Business Model, Unit Margins & SEC Financial Trajectory

ProQR Therapeutics N.V. (PRQR) is a NASDAQ-listed issuer in the Health Care sector, within the Biotechnology: Pharmaceutical Preparations industry. The company carries a market capitalization of $0.2B.

3. Institutional Bull vs. Bear Thesis & Valuation Tradeoff

  • 🐂 Primary Bull Case (D • RQD 44/100): Established market leader in Health Care with deep daily trading liquidity. Free cash flow yield of — and institutional whale pillar of 3/20. With Fundamental Cash Engine at 12/20 and Institutional Whale Flow at 3/20, sustained execution supports upside toward the upper end of the $1.20 – $2.65 52-week range.
  • 🐻 Primary Bear Case & Valuation Risk: Company executives have done more routine share selling than personal cash buying lately. Investors must weigh current valuation against — operating margins and a 1.00x macro beta.

4. 2nd-Order Butterfly Ripples & Key Questions to Watch

Upstream and downstream dependencies cannot be mapped from source data. Sector correlations beyond the Health Care classification and the beta of 1.

  • Key Question #1: Can PRQR sustain or expand its — operating margin and — ROIC against Biotechnology: Pharmaceutical Preparations peers over the next 4 quarters?
  • Key Question #2: Will free cash flow conversion (— FCF yield) strengthen balance-sheet liquidity (Altman Z-Score N/A) toward the $2.65 52-week high?
  • Key Question #3: How sensitive is PRQR's equity valuation to Health Care capital spending cycles and macro interest-rate shifts (Beta 1.00x)?

PRQR Live News Feed, Press Releases & Catalyst Wire

Real-time company headlines, analyst actions, and sector developments for ProQR Therapeutics N.V. (PRQR) • Click "Debate This Headline" to argue it in the Roar Pit below

💬 Jump to PRQR Debate Forum (3) ↓
🔥 THE ROAR PIT • LIVE COMMUNITY DEBATE 3 Active Posts & Replies

PRQR Bull vs. Bear Conversation Board — What's Your Call at $1.32?

🐂 67% BULLISH CONVICTION COMMUNITY TUG-OF-WAR ON PRQR 🐻 33% BEARISH CONVICTION
1. Pick Your Side on PRQR:
💡 Tip: Back up your call with a price target or RQD metric to get upvoted to the top.
MA MacroHawk_NYC RQD DEBATE OPENER • Cross-Asset Macro Desk 🐂 BULLISH 🎯 Target: $1.60 (+15.1%)
📌 Pinned Debate

Balance-sheet forensics score 13 of 20 with an Altman Z of 2.5 and Piotroski F of 6/9, indicating relative financial resilience.

Balance-sheet forensics score 13 of 20 with an Altman Z of 2.5 and Piotroski F of 6/9, indicating relative financial resilience.. When you look under the hood at PRQR, Fundamental Cash Engine is 12/20 with 0.0% gross margins and 0.0% ROIC. Bears are staring in the rearview mirror while institutional 13F flow (3/20) has been quietly accumulating below $2.81. My 12M target is $1.60.

VolSurface_Trader 🐂 BULL

Both sides have a point here — PRQR's 13/20 balance sheet score keeps downside contained, so the real swing factor next earnings call is backlog and FCF conversion.

RI RiskArb_Desk RQD DEBATE OPENER • Hedged Event Driven 🐻 BEARISH 🎯 Target: $1.14 (-18.0%)
Spot @ $1.39

ROIC and FCF yield are both 0%, and the cash-engine and insider-conviction pillars score 12 and 9 of 20, showing no earnings support.

Fading this rally in PRQR at $1.39. ROIC and FCF yield are both 0%, and the cash-engine and insider-conviction pillars score 12 and 9 of 20, showing no earnings support.. With a beta of 1.0 and the stock sitting at $1.39 (52-wk range $1.20–$2.81), the easy multiple expansion is already priced in.

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