TradingView report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
Why SHPH Stock dropped -3.88% Today — RQD Quant Desk Flash
Shuttle Pharmaceuticals Holdings Inc. (SHPH) carries a Roarable Rating of D- (Sell) with 41/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief)
Is SHPH stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-03, Shuttle Pharmaceuticals Holdings Inc. (NASDAQ: SHPH) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 41/100 at a spot price of $4.95 (-3.88% 1D, market cap $24.5M). Pillar breakdown: Fundamental Cash Engine 7/20, Institutional 13F & Options Flow 9/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 10/20, and Executive Insider Alignment 5/20. Active quantitative signal LIQUIDITY_TAILWIND (BULLISH, conviction undefined/100) notes: undefined.
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief)
How does SHPH compare to CRVO and CELU in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), SHPH carries a Roarable D- (41/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, CRVO (CervoMed Inc.) holds a E grade (28/100 RQD, P/E N/A, ROIC -35.0%, cap $24.2M) and CELU (Celularity Inc. (Class A)) posts a E grade (26/100 RQD, P/E N/A, ROIC -35.0%, cap $26.0M). Among the 5-stock peer group, SHPH leads on earnings multiple (N/A) while SHPH leads on capital efficiency (-35.0% ROIC).
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief)
What are the biggest fundamental strengths and SEC risk factors for SHPH?
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Per SHPH's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001757499), Shuttle Pharmaceuticals Holdings Inc. generated $33.4M in revenue (+54.8% YoY), -$11.7M in net income, and -$9.5M in free cash flow against $10.5M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 1/9
FRED Regime × Technicals: 6% of 52W Range • RSI-14 at 57.4 (BULLISH MOMENTUM)
Disciplined Float (+0.72% YoY Shares) & executive Form 4 sales trim 15 pts from alignment
⚔️ Adversarial Opposing Case: What Could Spark a SHPH Turnaround Squeeze
While SHPH currently carries a cautious 41/100 (D-) rating due to Insider Conviction & Share Dilution (5/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
Established market leader in Health Care with deep daily trading liquidity.
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($4.24) and Max Pain ($5.20) forces dealer call-delta covering toward $46.62.
Forensic Repair Trigger: Halting share dilution (Disciplined Float (+0.72% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
Why SHPH Stock dropped -3.88% Today — RQD Quant Desk Flash
Shuttle Pharmaceuticals Holdings Inc. (SHPH) dropped -3.88% to $4.95, trading at 6% of its 52-week range ($2.58 – $44.4). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 6% of its 52-week range ($2.58 – $44.4) with RSI-14 at 57.4 (BULLISH MOMENTUM).
- ▸Volatility Profile: Historical 20-day realized swing band of ±12.5% around $4.95 (no active unusual options sweep snapshot on file).
- ▸Primary SEC / Cross-Feed Trigger: SHPH Exhibits 2.77x True Net Liquidity Elasticity as Fed-TGA-RRP Prints $5,746B
ChartMill report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
Yahoo! Finance Canada report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
https://www.dars.gov.et/ report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
TradingKey report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
ChartMill report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
MarketBeat report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring SHPH)
- ✓Walkthrough of SHPH's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
- ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
SHPH Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. +54.8% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on SHPH today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for SHPH. Explore sector supply chains on /butterfly.
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (SHPH)
1. Head-to-Head Health Care Peer Comparison (SHPH vs. CRVO, CELU, MIRA, BYSI)
Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)Across 1015 tracked Health Care securities in the Roarable RQD universe, Shuttle Pharmaceuticals Holdings Inc. (SHPH) ranks #449 by composite RQD confidence (41/100, grade D-) and #817 by equity capitalization ($24.5M). Within this direct 5-issuer industry benchmark cohort, SHPH leads on earnings valuation at N/A trailing P/E, while SHPH leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. SHPH currently leads its immediate peer cohort in composite quantitative strength at 41/100 (D-).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| SHPH
ACTIVE
Shuttle Pharmaceuticals Holdings Inc. | D- | 41/100 | — | — | -35.0% | -3.88% | $24.5M | Benchmark Subject |
| CRVO CervoMed Inc. | E | 28/100 | — | — | -35.0% | +2.50% | $24.2M | /crvo-vs-shph → |
| CELU Celularity Inc. (Class A) | E | 26/100 | — | 24.4% | -35.0% | +0.30% | $26.0M | /celu-vs-shph → |
| MIRA MIRA Pharmaceuticals Inc. | D- | 36/100 | — | — | -35.0% | -2.06% | $23.0M | /mira-vs-shph → |
| BYSI BeyondSpring Inc. | D- | 37/100 | — | — | -35.0% | +25.18% | $26.5M | /bysi-vs-shph → |
2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)
SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001757499 ↗In its most recent audited fiscal period (FY2025, filed 2025-12-31), Shuttle Pharmaceuticals Holdings Inc. (SHPH) reported GAAP revenue of $33.4M (+54.8% vs. FY2024 revenue of $21.5M , and +102.2% cumulative change since FY2023) , GAAP net income of -$11.7M, operating cash flow of -$9.5M, and free cash flow of -$9.5M (-29.4% YoY). On the balance sheet, SHPH closed FY2025 with $10.5M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 1/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $33.4M | -$11.7M | -$9.5M | -$9.5M | $10.5M | — |
| FY2024 (FY) | 2024-12-31 | $21.5M | -$9.1M | -$7.3M | -$7.3M | $2.5M | — |
| FY2023 (FY) | 2023-12-31 | $16.5M | -$6.6M | -$5.6M | -$5.6M | — | — |
3. SHPH Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs SHPH stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-03, Shuttle Pharmaceuticals Holdings Inc. (NASDAQ: SHPH) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 41/100 at a spot price of $4.95 (-3.88% 1D, market cap $24.5M). Pillar breakdown: Fundamental Cash Engine 7/20, Institutional 13F & Options Flow 9/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 10/20, and Executive Insider Alignment 5/20. Active quantitative signal LIQUIDITY_TAILWIND (BULLISH, conviction undefined/100) notes: undefined.
How does SHPH compare to CRVO and CELU in the Health Care sector?
Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), SHPH carries a Roarable D- (41/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, CRVO (CervoMed Inc.) holds a E grade (28/100 RQD, P/E N/A, ROIC -35.0%, cap $24.2M) and CELU (Celularity Inc. (Class A)) posts a E grade (26/100 RQD, P/E N/A, ROIC -35.0%, cap $26.0M). Among the 5-stock peer group, SHPH leads on earnings multiple (N/A) while SHPH leads on capital efficiency (-35.0% ROIC).
What are the biggest fundamental strengths and SEC risk factors for SHPH?
Per SHPH's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001757499), Shuttle Pharmaceuticals Holdings Inc. generated $33.4M in revenue (+54.8% YoY), -$11.7M in net income, and -$9.5M in free cash flow against $10.5M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Where is SHPH trading relative to its 50-day, 200-day, and 52-week technical levels?
SHPH last traded at $4.95 (-3.88% on volume of 92,223 shares), positioning the stock +16.75% above its 50-day simple moving average ($4.24) and -28.78% below its 200-day simple moving average ($6.95). Across its 52-week range of $2.58 to $44.40, SHPH sits at the 5.7% percentile with a 14-day RSI of 57.4 (BULLISH MOMENTUM) and an implied next-earnings move of ±12.5% ($4.33 to $5.57).
SHPH — Shuttle Pharmaceuticals Holdings Inc.: What the Facts Mean to a Prospective Investor
1. Roarable Rating Brief: What This Means to a Prospective Investor
Shuttle Pharmaceuticals Holdings Inc. (SHPH) earns a live Roarable RQD composite score of 41/100, corresponding to a D- letter grade (Roarable Sell) at a spot price of $4.95 (-3.88% 1D, market capitalization $24.5M).
- Fundamental Cash Engine (7/20): Anchored by return on invested capital (ROIC) of -35.0%, gross margin of —, operating margin of —, and free cash flow yield of —.
- Whale 13F & Options Flow (9/20) + Insider Conviction (5/20): Tracks institutional 13F accumulation, CBOE options call/put positioning, and SEC Form 4 / Congressional PTR filings.
- Macro Regime Fit (10/20) + Forensic Balance Sheet (10/20): Incorporates a 1.00x equity beta, Altman Z-Score of N/A, Piotroski F-Score of 1/9, and Debt/Equity of N/A.
2. Business Model, Unit Margins & SEC Financial Trajectory
Shuttle Pharmaceuticals Holdings Inc. Is a NASDAQ-listed issuer in the Health Care sector, within the Biotechnology: Pharmaceutical Preparations industry. The profile does not describe its products, customers, or revenue model. Reported revenue is — for each of FY 2025, FY 2024, and FY 2023. —: product pipeline, end customers, and monetization mechanism.
In its latest audited SEC EDGAR 10-K filing for FY2025 (filed 2025-12-31), Shuttle Pharmaceuticals Holdings Inc. (SHPH) reported $33.4M in annual revenue (up from $21.5M in FY2024, +54.8% YoY) and -$11.7M in GAAP net income. Over the multi-year SEC filing window from FY2023 ($16.5M revenue, -$6.6M net income) through FY2025, SHPH scaled operating cash flow to -$9.5M and free cash flow to -$9.5M, backed by $10.5M in total assets against $0 in total debt.
3. Institutional Bull vs. Bear Thesis & Valuation Tradeoff
- 🐂 Primary Bull Case (D- • RQD 41/100): Established market leader in Health Care with deep daily trading liquidity. Free cash flow yield of — and institutional whale pillar of 9/20. With Fundamental Cash Engine at 7/20 and Institutional Whale Flow at 9/20, sustained execution supports upside toward the upper end of the $2.58 – $44.40 52-week range.
- 🐻 Primary Bear Case & Valuation Risk: Company executives have done more routine share selling than personal cash buying lately. Investors must weigh current valuation against — operating margins and a 1.00x macro beta.
4. 2nd-Order Butterfly Ripples & Key Questions to Watch
Per the Butterfly graph, supply_chain is NONE and butterfly_links is empty, so no upstream or downstream dependencies are mapped. —: supplier, customer, and partner relationships. The only sector context is Health Care / Biotechnology: Pharmaceutical Preparations. Investors should watch the auditor transition as a 2nd-order governance bottleneck, since an unfilled audit role could delay reporting. The liquidity beta is a macro sensitivity rather than an operating linkage, and its weak correlation limits its predictive use.
- Key Question #1: Can SHPH sustain or expand its — operating margin and -35.0% ROIC against Biotechnology: Pharmaceutical Preparations peers over the next 4 quarters?
- Key Question #2: Following FY2025 revenue of $33.4M and free cash flow of -$9.5M, how will capital allocation balance growth reinvestment against $0 in total debt?
- Key Question #3: How sensitive is SHPH's equity valuation to Health Care capital spending cycles and macro interest-rate shifts (Beta 1.00x)?
SHPH Live News Feed, Press Releases & Catalyst Wire
Real-time company headlines, analyst actions, and sector developments for Shuttle Pharmaceuticals Holdings Inc. (SHPH) • Click "Debate This Headline" to argue it in the Roar Pit below
TradingView report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
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Stock Titan report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
Yahoo! Finance Canada report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
https://www.dars.gov.et/ report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
TradingKey report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
ChartMill report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
MarketBeat report covering Shuttle Pharmaceuticals Holdings Inc. (SHPH) market action, institutional positioning, and fundamental catalysts.
SHPH Bull vs. Bear Conversation Board — What's Your Call at $4.95?
The Butterfly graph flags a BULLISH liquidity tailwind with a Macro Tailwind Score of 90/100, though its correlation is weak (r = -0.16
Picked up a starter position in SHPH in my $100K Virtual Cash book at $5.15. The Butterfly graph flags a BULLISH liquidity tailwind with a Macro Tailwind Score of 90/100, though its correlation is weak (r = -0.16).. Trading inside a $2.58–$44.40 52-week range with 0.0% FCF yield gives solid downside support if Biotechnology: Pharmaceutical Preparations multiples expand this quarter.
Both sides have a point here — SHPH's 10/20 balance sheet score keeps downside contained, so the real swing factor next earnings call is backlog and FCF conversion.
With zero reported revenue, ROIC of -35%, FCF of -$9.5M in FY 2025, and an auditor exit pending, the balance sheet and cash flow are we
Here is the bear case nobody on the bull side wants to address on SHPH: With zero reported revenue, ROIC of -35%, FCF of -$9.5M in FY 2025, and an auditor exit pending, the balance sheet and cash flow are weak.. At current EV/EBITDA multiples, even a small guidance miss in Biotechnology: Pharmaceutical Preparations triggers a 12-15% air pocket.