IRulya Therapeutics Inc. (IRLA) — RQD Stock Rating Cockpit

$32.95 +4.21% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $33.14

IRulya Therapeutics Inc. (IRLA) carries a Roarable Rating of E (Strong Sell) with 33/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.

ROARABLE E • RED ALERT Cap $342.8M
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🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief) Is IRLA stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-02, IRulya Therapeutics Inc. (NASDAQ: IRLA) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 33/100 at a spot price of $32.95 (+4.21% 1D, market cap $342.8M). Pillar breakdown: Fundamental Cash Engine 7/20, Institutional 13F & Options Flow 6/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 7/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, IRLA ranks #740 in composite RQD confidence.

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🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief) How does IRLA compare to XFOR and ALEC in the Health Care sector?
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Within the Health Care sector (Biotechnology: Biological Products (No Diagnostic Substances)), IRLA carries a Roarable E (33/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, XFOR (X4 Pharmaceuticals Inc.) holds a E grade (29/100 RQD, P/E N/A, ROIC -35.0%, cap $333.1M) and ALEC (Alector Inc.) posts a E grade (33/100 RQD, P/E N/A, ROIC -35.0%, cap $332.1M). Among the 5-stock peer group, IRLA leads on earnings multiple (N/A) while IRLA leads on capital efficiency (-35.0% ROIC).

✓ Pre-computed one-to-many AI Quant brief
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for IRLA?
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Per IRLA's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001662774), IRulya Therapeutics Inc. generated $0 in revenue, -$84.0M in net income, and -$41.8M in free cash flow against $93.5M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

✓ Pre-computed one-to-many AI Quant brief
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INTERACTIVE SCENARIO DECK:
🛡️ Portfolio Crash X-Ray
EXT / AFTER-HRS: $33.14 (+0.57%)🧬 Dilution Drag (+2.48% YoY Shares)⚙️ Cash Engine: 7/20 (D-) • 0% FCF Margin
Verify 90D Bucket Audit →
📊 Historical Track Record Warning: Scores below 50 (33/100 · E) historically underperformed SPY in 71% of rolling 90-day windows (-8.9% avg 90D alpha vs SPY • 29.0% hit rate).
Audit Bucket Track Record →
RQD QUANT TACHOMETERRED ALERT • E
025507510033
3-of-3 JEV AI Jury Bearish Warning
Cash
SEC
Whale

Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR SNOWFLAKE RADARRw E · Rk D-
Cash (7)Whales (6)SEC (10)Macro (7)CEO (3)
Each axis scored 0–20
12M PRICE TARGET CONE-11.3% Base Target
$956 Bull$29 Base$23 Bear
📬 FREE IRLA RATING-CHANGE & BRIEFING ALERTSManage / Unsubscribe
WHALE OPTIONS SNAPSHOT: — (No Active Options Snapshot on file for IRLA)Realized 20D OHLCV Swing Band: ±12.5%
Deterministic 5-Pillar Attribution (33/100 Composite)
🔍 WHY IRLA SCORES 33/100 (E) — TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag
▲ #1 Bullish Driver: SEC 10-K Forensic Risk+10/20 pts (30% of score)

Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 1/9

▲ #2 Bullish Driver: Cash Engine Quality+7/20 pts (21% of score)

SEC XBRL FY 2025 (10-K): 0% FCF Margin ($0 FCF) & 52% Gross Margin

▼ #1 Drag / Risk Factor: Insider Conviction & Share Dilution4/20 pts (-16 pt drag)

Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment

📈 PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 → Q2 → Q3 → Current
Q1 (-3Q)
25
Grade E$32.40+6.3% Next Q
Q2 (-2Q)
28
Grade E$34.45-8.9% Next Q
Q3 (-1Q)
30
Grade E$31.38+5% Next Q
Current
33
Grade E$32.95-8.9% Hist 90D α
Trajectory: E (25) → E (33)Full Audit →
⚔️ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER

⚔️ Adversarial Opposing Case: What Could Spark a IRLA Turnaround Squeeze

Gideon Ashmere Forensic Desk →

While IRLA currently carries a cautious 33/100 (E) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.

🚀 Contrarian Squeeze Trigger #1

Established market leader in Health Care with deep daily trading liquidity.

🚀 Contrarian Squeeze Trigger #2

Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($31.02) and Max Pain ($34.60) forces dealer call-delta covering toward $955.50.

🚀 Contrarian Squeeze Trigger #3

Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.

🎲 LIVE PREDICTION MARKET ODDS TIED TO $IRLA• $2.4M Crowd Pool • Kalshi / Polymarket Composite
Contract: “IRLA Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMA”
RSI-14 MOMENTUMNEUTRAL RANGE
49.730 Oversold · 70 Hot
ALTMAN-Z SHIELDFORTRESS SAFE (>3.0)
3.80>3.0 Fortress Safe
PIOTROSKI F-SCOREWEAK QUALITY (1–4)
1 / 99-Pt Accounting
52-WEEK LASER RANGE2% OF RANGE
L: $15$32.95H: $910
1. Money & Cash Health● WEAK
Are profits real cash in the bank?

Weak cash conversion or heavy valuation strain compared to actual cash earned.

Factor Grade: D-RQD 7 / 20
2. Big Money & Insiders● TRIMMING
Are whales & executives buying or selling?

Insiders and big institutional desks have been trimming shares rather than stepping up to buy.

Factor Grade: ERQD 9 / 40
3. Hidden Risks & Market Weather● WARNING
SEC fine-print scan & interest-rate fit

High sensitivity to tight interest rates or new risk warnings added to recent SEC annual filings.

Factor Grade: D-RQD 17 / 40
MULTI-MODEL JEV QUANT JURY DELIBERATION

3-of-3 JEV AI Jury Bearish Warning on IRLA

Cash & Moat Bull AI
ROIC & Free Cash Flow Model
BEARISH (35)

-35.0% ROIC with 42.0% gross margin and -12.19% FCF yield.

SEC Forensic Auditor AI
10-K Accruals & Altman-Z Guard
BEARISH (50)

Altman-Z 4.20 and Piotroski 1/9 pass balance-sheet audit.

Whale & Macro Hawk AI
Options Skew, 13F & Fed NetLiq
BEARISH (27)

9/40 institutional & smart-money positioning score with 7/20 macro alignment.

Bull Case: Why Buyers Like IRLA
  • ✓Established market leader in Health Care with deep daily trading liquidity.
Bear Case: What Could Go Wrong
  • !Company executives have done more routine share selling than personal cash buying lately.
  • !Sensitive to high interest rates and tighter Federal Reserve market liquidity.
  • !Recent SEC filings added new risk-factor disclosures that warrant keeping an eye on margins.
ON-DEMAND RQD QUANT WORKSHOP • SPONSORED / PARTNER SPOTLIGHTHosted by Perry Belcher & Roarable Forensic Quant Desk

Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring IRLA)

  • ✓Walkthrough of IRLA's RQD Radar, SEC cash-conversion gap & downside invalidation levels
  • ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
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IRLA // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: +35.04%▲ ASCENDING CHANNEL
2026-11-02O $32.95H $32.95L $31.62C $32.95VOL 64.3K
RES: $42.12SUP: $27.08SMA50: $31.02SMA200: $51.74
$332.2$246.3$160.3$74.37$-11.57RES $42.12SUP $27.08$32.952026-05-042026-06-172026-08-042026-09-172026-11-02
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

IRLA Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

Share Count & Dilution Monitor (#25)

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle (#30)
8.0%/yr Implied 5Y Growth

vs. +6.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger (#33)

No active Ellis Vennor swing setup published on IRLA today. View full Setup Ledger →

🦋 Documented & Second-Order Butterfly Connections Open Graph →

No direct multi-tier Butterfly edges indexed yet for IRLA. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video
🎬 No recent verified company-specific video clip queued for IRLA today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk →
DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK

📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (IRLA)

Health Care Rank #740 of 1016 ⚔️ XFOR vs IRLA Full Matrix →

1. Head-to-Head Health Care Peer Comparison (IRLA vs. XFOR, ALEC, SCTX, KYTX)

Industry: Biotechnology: Biological Products (No Diagnostic Substances) (156 Tracked Issuers)

Across 1016 tracked Health Care securities in the Roarable RQD universe, IRulya Therapeutics Inc. (IRLA) ranks #740 by composite RQD confidence (33/100, grade E) and #504 by equity capitalization ($342.8M). Within this direct 5-issuer industry benchmark cohort, IRLA leads on earnings valuation at N/A trailing P/E, while IRLA leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. SCTX currently holds the highest overall quantitative score in the immediate peer group at 44/100 (D) compared with IRLA at 33/100 (E).

Ticker / Company Roarable Grade RQD Score Trailing P/E Gross Margin ROIC 1D Change Market Cap Head-to-Head
IRLA ACTIVE
IRulya Therapeutics Inc.
E 33/100 — — -35.0% +4.21% $342.8M Benchmark Subject
XFOR
X4 Pharmaceuticals Inc.
E 29/100 — 83.6% -35.0% -0.30% $333.1M /xfor-vs-irla →
ALEC
Alector Inc.
E 33/100 — — -35.0% -1.34% $332.1M /alec-vs-irla →
SCTX
Scribe Therapeutics Inc.
D 44/100 — — — -11.58% $330.2M /sctx-vs-irla →
KYTX
Kyverna Therapeutics Inc.
D- 35/100 — — -35.0% -3.08% $361.8M /kytx-vs-irla →

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)

SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001662774

In its most recent audited fiscal period (FY2025, filed 2025-12-31), IRulya Therapeutics Inc. (IRLA) reported GAAP revenue of $0 (N/A vs. FY2024 revenue of $0 ) , GAAP net income of -$84.0M, operating cash flow of -$41.4M, and free cash flow of -$41.8M (-29.9% YoY). On the balance sheet, IRLA closed FY2025 with $93.5M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 1/9).

Fiscal Period Filing Date Revenue Net Income Operating Cash Flow Free Cash Flow Total Assets Total Debt
FY2025 (FY) 2025-12-31 $0 -$84.0M -$41.4M -$41.8M $93.5M —
FY2024 (FY) 2024-12-31 $0 -$56.8M -$31.9M -$32.2M $114.5M —
FY2023 (FY) 2023-12-31 $0 -$31.4M -$18.3M -$18.3M — —

3. IRLA Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is IRLA stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

As of 2026-11-02, IRulya Therapeutics Inc. (NASDAQ: IRLA) is rated E (Strong Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 33/100 at a spot price of $32.95 (+4.21% 1D, market cap $342.8M). Pillar breakdown: Fundamental Cash Engine 7/20, Institutional 13F & Options Flow 6/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 7/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, IRLA ranks #740 in composite RQD confidence.

How does IRLA compare to XFOR and ALEC in the Health Care sector?

Within the Health Care sector (Biotechnology: Biological Products (No Diagnostic Substances)), IRLA carries a Roarable E (33/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, XFOR (X4 Pharmaceuticals Inc.) holds a E grade (29/100 RQD, P/E N/A, ROIC -35.0%, cap $333.1M) and ALEC (Alector Inc.) posts a E grade (33/100 RQD, P/E N/A, ROIC -35.0%, cap $332.1M). Among the 5-stock peer group, IRLA leads on earnings multiple (N/A) while IRLA leads on capital efficiency (-35.0% ROIC).

What are the biggest fundamental strengths and SEC risk factors for IRLA?

Per IRLA's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001662774), IRulya Therapeutics Inc. generated $0 in revenue, -$84.0M in net income, and -$41.8M in free cash flow against $93.5M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

Where is IRLA trading relative to its 50-day, 200-day, and 52-week technical levels?

IRLA last traded at $32.95 (+4.21% on volume of 98,017 shares), positioning the stock +6.22% above its 50-day simple moving average ($31.02) and -36.32% below its 200-day simple moving average ($51.74). Across its 52-week range of $15.10 to $910.00, IRLA sits at the 2.0% percentile with a 14-day RSI of 49.7 (NEUTRAL RANGE) and an implied next-earnings move of ±12.5% ($28.83 to $37.07).

IRLA Investor FAQ & Complete 8-Part Research Index

100% OPEN ACCESS • SEC EDGAR × CBOE × FRED

Should I buy, hold, or sell IRLA stock right now?

IRulya Therapeutics Inc. (IRLA) currently earns a Roarable Rating of E (Strong Sell — SELL) with 33/100 RQD Confidence. Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.

What is IRLA's 12-month price target and RQD AI Jury consensus?

IRLA's 12-month base price target is $29.24 (range $22.81 to $955.5), backed by transparent SEC XBRL cash-flow, Form 4 insider, and CBOE options flow analysis.

ROARABLE RATING BRIEF • RQD 33/100 (E) ✓ STAGE-C NUMBER FIREWALL VERIFIED

IRLA — IRulya Therapeutics Inc.: What the Facts Mean to a Prospective Investor

Engine: anthropic/claude-haiku-5.5
As of: 2026-11-02T15:38:08Z

Roarable Rating Brief: What This Means to a Prospective Investor

Per the Roarable RQD rating, IRLA scores 33 out of 100 with a letter grade of E, labeled "Roarable Strong Sell — Forensic Risk / Avoid." The fundamental cash engine pillar scores 7 out of 20, reflecting an ROIC of -35% and an FCF yield of -12.19%, which indicates the business is consuming rather than generating cash on a per-dollar-of-capital basis. The whale 13F flow pillar scores 6 out of 20, based on institutional accumulation and options positioning, signaling limited smart-money conviction. The insider conviction pillar scores 3 out of 20, the lowest of the five, drawn from SEC Form 4 and Congressional PTR cluster flow. The macro regime fit pillar scores 7 out of 20, with a beta of 1.0 and sector sensitivity noted. The forensic balance sheet pillar scores 10 out of 20, with an Altman Z-Score of 2.5, a Piotroski F-Score of 1/9, and a Debt/Equity ratio of 0.5.

For a prospective investor evaluating the stock today, the rating points toward downside risk concentrated in the cash-flow and insider-conviction pillars. The forensic balance sheet metrics, particularly the Piotroski F-Score of 1 out of 9, indicate weak financial-health signals across the fundamentals checklist. Any upside case would need to rest on factors outside the reported cash engine, which the source data does not establish. This analysis is educational and not personalized financial advice.

Business

IRulya Therapeutics Inc. is a NASDAQ-listed issuer in the Health Care sector, operating in the Biotechnology: Biological Products (No Diagnostic Substances) industry. Per the profile, the company carries a market capitalization of $0.3B. Per the recent news wire, the company was formerly known as Quince Therapeutics and has repositioned toward pulmonary and lung disease drug development. The source data does not describe specific products, customers, or revenue model beyond reporting zero revenue in the financials.

Financial Trend

PeriodRevenueOperating IncomeNet IncomeEPSFCFCashDebt
FY 2025$0.0M$-58.1M$-84.0MN/A$-41.8M$5.8MN/A
FY 2024$0.0M$-57.3M$-56.8MN/A$-32.2M$6.2MN/A
FY 2023$0.0M$-34.6M$-31.4MN/A$-18.3MN/AN/A

Per the SEC financials, reported revenue is $0.0M across all three periods, with operating losses widening from $-34.6M in FY 2023 to $-58.1M in FY 2025 and net losses from $-31.4M to $-84.0M. Per the market data, gross, operating, and net margins are each 0%, and ROIC is -35%. Per the Roarable RQD rating, the Altman Z-Score is 2.5 and the Piotroski F-Score is 1 out of 9, with a Debt/Equity ratio of 0.5. Reported cash declined from $6.2M in FY 2024 to $5.8M in FY 2025 against negative free cash flow of $-41.8M in FY 2025.

Recent Catalysts & News Wire Analysis

Per the recent news wire, the headline catalyst is the rename from Quince Therapeutics to IRulya Therapeutics, described as advancing pulmonary drug development after a merger. A Fierce Pharma item characterizes the relaunch as going all in on lung disease following what it calls a Hail Mary merger. Six items all carry a YELLOW light and a MARKET WIRE impact label, and the summaries are generic market-action descriptions rather than verifiable event detail. Recurring themes are the name change, lung-disease focus, and merger context. Risk watch items include the absence of revenue, widening losses, and the thin cash balance relative to annual cash burn shown in the financials. Per the Butterfly Supply-Chain Graph, no supply-chain links or proprietary signals are recorded.

Open Questions

  • What is the company's cash runway given FY 2025 free cash flow of $-41.8M against reported cash of $5.8M?
  • What were the terms and financial impact of the merger referenced in the news wire, and how does it affect the balance sheet?
  • Which clinical or regulatory milestones underpin the pulmonary pipeline, and what is their timing?
  • Why are FY 2023 cash and debt figures, and FY 2024 and FY 2025 debt, not reported in the source data?
  • What explains the 52-week range of $15.1 to $910, which the source data does not reconcile with the current price of 31.62?

IRLA Live News Feed, Press Releases & Catalyst Wire

Real-time company headlines, analyst actions, and sector developments for IRulya Therapeutics Inc. (IRLA) • Click "Debate This Headline" to argue it in the Roar Pit below

💬 Jump to IRLA Debate Forum (3) ↓
🔥 THE ROAR PIT • LIVE COMMUNITY DEBATE 3 Active Posts & Replies

IRLA Bull vs. Bear Conversation Board — What's Your Call at $32.95?

🐂 33% BULLISH CONVICTION COMMUNITY TUG-OF-WAR ON IRLA 🐻 67% BEARISH CONVICTION
1. Pick Your Side on IRLA:
💡 Tip: Back up your call with a price target or RQD metric to get upvoted to the top.
RO RoarDesk_Moderator Roarable Research Desk 🐻 BEARISH 🎯 Target: $27.83 (-12.0%)
📌 Pinned Debate

🔥 Official Bull vs. Bear Debate: Is IRLA (E • RQD 33/100) a Buy at $31.62?

Welcome to the IRLA (IRulya Therapeutics Inc.) Roar Pit. Current RQD Composite is 33/100 (Roarable Strong Sell — Forensic Risk / Avoid) in Biotechnology: Biological Products (No Diagnostic Substances). Bulls point to operating leverage and sector positioning, while bears focus on macro rate sensitivity and margin execution. Pick your side (🐂 Bull or 🐻 Bear) and drop your price target below.

SK SkepticalCFA Forensic Accounting Watch 🐻 BEARISH 🎯 Target: $26.24 (-17.0%)
Spot @ $31.62

Pump the brakes on IRLA — check the valuation vs. margin headwinds

Everyone in here is repeating the bull case on IRLA, but look at what you are paying: current EV/EBITDA multiples with tightening sector spreads. Unless IRulya Therapeutics Inc. expands free cash flow yield next quarter, I would rather wait for a pullback closer to the 200-day moving average before touching this.

SI SiliconVal_Bull Verified K Arena Trader 🐂 BULLISH 🎯 Target: $39.53 (+25.0%)
Spot @ $31.62

IRLA cash flow & RQD setup is being underpriced by the Street here

Looking at the 5-pillar RQD breakdown on IRLA, the market is fixating on short-term headline noise in Biotechnology: Biological Products (No Diagnostic Substances) and ignoring the balance sheet and cash flow trajectory. At $31.62 (52-wk range $15.10 - $910.00), any beat on forward guidance forces shorts and underweight funds to chase.

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